Stat2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stat2
signal transducer and activator of transcription 2
MGI:103039

10 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Stat2^m1Btlr/Stat2^m1Btlr C57BL/6J-Stat2^m1Btlr	decreased CD8-positive, alpha-beta T cell number	J:265265
	decreased central memory CD8 positive, alpha-beta T cell number	J:265265
	decreased single-positive T cell number	J:265265
Stat2^p117/Stat2^p117 C57BL/6J-Stat2^P117	abnormal level of surface class II molecules	J:164049
	decreased dendritic cell number	J:164049
	decreased level of surface class I molecules	J:164049
	decreased plasmacytoid dendritic cell number	J:164049
	increased susceptibility to Picornaviridae infection induced morbidity/mortality	J:164049
Stat2^tm1Shnd/Stat2^tm1Shnd involves: 129S1/Sv * 129X1/SvJ	abnormal T cell differentiation	J:66564
Stat2^tm1Shnd/Stat2^tm1Shnd involves: 129S1/Sv * 129X1/SvJ	increased susceptibility to Riboviria infection	J:66564

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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