Reln Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Reln
reelin
MGI:103022

80 phenotypes from 15 alleles in 22 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Reln^em1(IMPC)Mbp/Reln⁺ C57BL/6N-Reln^em1(IMPC)Mbp/MbpMmucd	abnormal lymph node morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal uterus morphology	J:211773
	enlarged lymph nodes	J:211773
	enlarged spleen	J:211773
	hydrometra	J:211773
Reln^em1(IMPC)Mbp/Reln^em1(IMPC)Mbp C57BL/6N-Reln^em1(IMPC)Mbp/MbpMmucd	female infertility	J:211773
	male infertility	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Reln^m1Anu/Reln^m1Anu C57BL/6JAnu-Reln^m1Anu	decreased body size	J:104190
Reln^m1Anu/Reln^m1Anu C57BL/6JAnu-Reln^m1Anu	impaired coordination	J:104190
Reln^rl-2J/Reln^rl-2J involves: C3H * C57BL/6J * DBA/2J	abnormal cone electrophysiology	J:71970
	abnormal retina inner nuclear layer morphology	J:71970
	abnormal retina rod bipolar cell morphology	J:71970
	abnormal rod electrophysiology	J:71970
Reln^rl-4J/Reln^rl-4J B6.Cg-Reln^rl-4J/GrsrJ	abnormal cerebellar cortex morphology	J:133649
	abnormal cerebellar granule layer morphology	J:133649
	abnormal cerebellar Purkinje cell layer	J:133649
	abnormal gait	J:133649
	abnormal hippocampus layer morphology	J:133649
	abnormal stratification in cerebral cortex	J:133649
	ataxia	J:133649
	decreased body size	J:133649
	impaired balance	J:133649
	postnatal lethality, incomplete penetrance	J:133649
	small cerebellum	J:133649
Reln^rl-5J/Reln^rl-5J C3Fe(SWV) Mbp^shi-Reln^rl-5J/GrsrJ	abnormal cortical marginal zone morphology	J:98756
	abnormal hippocampus layer morphology	J:98756
	abnormal stratification in cerebral cortex	J:98756
	ataxia	J:98756
	delaminated cerebellar granule layer	J:98756
	delaminated Purkinje cell layer	J:98756
	small cerebellum	J:98756
Reln^rl-6J/Reln^rl-6J C57BL/6J-Reln^rl-6J/J	abnormal cerebellum development	J:87349
	abnormal stratification in cerebral cortex	J:87349
	muscle spasm	J:87349
	small cerebellum	J:87349
	tremors	J:87349
Reln^rl-7J/Reln^rl-7J C57BL/6J-Reln^rl-7J/GrsrJ	abnormal cerebellar Purkinje cell layer	J:125130
	abnormal cerebral cortex morphology	J:125130
	abnormal gait	J:125130
	abnormal hippocampus morphology	J:125130
	abnormal stratification in cerebral cortex	J:125130
	ataxia	J:125130
	impaired balance	J:125130
	premature death	J:125130
	small cerebellum	J:125130
Reln^rl-8J/Reln^rl-8J STOCK Reln^rl-8J/J	abnormal cerebellar cortex morphology	J:142871
	abnormal cerebral cortex morphology	J:142871
	abnormal dentate gyrus morphology	J:142871
	abnormal gait	J:142871
	abnormal hippocampus morphology	J:142871
	abnormal motor capabilities/coordination/movement	J:142871
	ataxia	J:142871
	impaired righting response	J:142871
	premature death	J:142871
	small cerebellum	J:142871
Reln^rl-Alb2/Reln^rl-Alb2 involves: C3H/HeJ * C57BL/6J	impaired righting response	J:41458
Reln^rl-Alb2/Reln^rl-Alb2 involves: C3H/HeJ * C57BL/6J	tremors	J:41458
Reln^rl-Alb/Reln^rl-Alb involves: 101 * C3Hf/Rl	abnormal cerebellum external granule cell layer morphology	J:27506
	abnormal Purkinje cell morphology	J:27506
	ataxia	J:27506
	decreased body size	J:27506
	decreased Purkinje cell number	J:27506
	decreased survivor rate	J:27506
	ectopic Purkinje cell	J:27506
	small cerebellum	J:27506
	tremors	J:27506
Reln^rl-od/Reln^rl-od involves: C57BL/6 * DBA/2	abnormal cerebellar Purkinje cell layer	J:79979
	abnormal dentate gyrus morphology	J:79979
	abnormal hippocampus morphology	J:79979
	abnormal motor coordination/balance	J:79979
	abnormal stratification in cerebral cortex	J:79979
	ataxia	J:79979
	decreased body weight	J:79979
	decreased locomotor activity	J:79979
	postnatal growth retardation	J:79979
	postnatal lethality	J:79979
	tremors	J:79979
Reln^rl-Orl/Reln^rl-Orl BALB/c-Reln^rl-Orl	abnormal olfactory bulb granule cell layer morphology	J:121846
	abnormal olfactory bulb morphology	J:121846
	abnormal postnatal subventricular zone morphology	J:121846
	abnormal rostral migratory stream morphology	J:121846
Reln^rl-tg/Reln^rl-tg involves: C3H * C57BL/6 * DBA/2	abnormal cerebellar cortex morphology	J:21534
	abnormal gait	J:21534
	abnormal hippocampus granule cell layer	J:21534
	abnormal hippocampus pyramidal cell layer	J:21534
	abnormal posture	J:21534
	absent cerebellar foliation	J:21534
	ataxia	J:21534
	small cerebellum	J:21534
	tremors	J:21534
Reln^rl/Reln⁺ B6.Cg-Reln^rl	abnormal prepulse inhibition	J:223944
	abnormal short-term spatial reference memory	J:223944
	abnormal social investigation	J:223944
Reln^rl/Reln⁺ B6C3Fe a/a-Reln^rl/J	abnormal ventral striatum morphology	J:107996
Reln^rl/Reln⁺ B6C3Fe a/a-Reln^rl/J	decreased dopaminergic neuron number	J:107996
Reln^rl/Reln⁺ involves: BALB/c	decreased Purkinje cell number	J:42417
	normal nervous system phenotype	J:42417
	Purkinje cell degeneration	J:42417
	small cerebellum	J:42417
Reln^rl/Reln^rl B6.Cg-Reln^rl	abnormal dentate gyrus morphology	J:5312
	abnormal entorhinal cortex morphology	J:5312
	abnormal gait	J:5312
	abnormal hippocampus CA1 region morphology	J:5312
	abnormal hippocampus CA2 region morphology	J:5312
	abnormal hippocampus morphology	J:5312
	abnormal olfactory cortex morphology	J:5312
	abnormal sensory neuron innervation pattern	J:5312
	ataxia	J:5312
	decreased body weight	J:5312
	decreased locomotor activity	J:5312
	impaired righting response	J:5312
	infertility	J:5312
	postnatal growth retardation	J:5312
	premature death	J:5312
	tremors	J:5312
Reln^rl/Reln^rl C3.Cg-Reln^rl	abnormal cerebral cortex morphology	J:12728
	abnormal dentate gyrus morphology	J:5312
	abnormal entorhinal cortex morphology	J:5312
	abnormal hippocampus CA1 region morphology	J:5312
	abnormal hippocampus CA2 region morphology	J:5312
	abnormal hippocampus morphology	J:5312
	abnormal neuronal migration	J:12728
	abnormal olfactory cortex morphology	J:5312
	abnormal sensory neuron innervation pattern	J:5312
	abnormal stratification in cerebral cortex	J:12728
	ataxia	J:5312
	normal behavior/neurological phenotype	J:5312
	diarrhea	J:5312
	postnatal growth retardation	J:5312
	premature death	J:5312
	slow postnatal weight gain	J:5312
Reln^rl/Reln^rl involves: 129S4/SvJaeSor * C57BL/6J	abnormal cortical marginal zone morphology	J:74239
	abnormal dentate gyrus morphology	J:74239
	abnormal hippocampus pyramidal cell layer	J:74239
Reln^rl/Reln^rl involves: BALB/c	abnormal sexual interaction	J:14535
Reln^rl/Reln^rl involves: C3HeB/FeJ * C57BL/6J	abnormal cerebellum morphology	J:12728
	abnormal cerebral cortex morphology	J:12728
	abnormal neuron differentiation	J:12728
	small cerebellum	J:12728
Reln^rl/Reln^rl Not Specified	abnormal gait	J:13038
	decreased body size	J:13038
	decreased locomotor activity	J:13038
	disheveled coat	J:13038
	impaired balance	J:13038
	lethality at weaning, complete penetrance	J:13038
	male infertility	J:13038
	postnatal growth retardation	J:13038
	reduced female fertility	J:13038
	tremors	J:13038
Reln^rl/Reln^rl Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw involves: BALB/c * C57BL/6 * C57BL/6J	abnormal axon extension	J:168258
Reln^tm1.1Mhat/Reln^tm1.1Mhat B6NSlc.B6(Cg)-Reln^tm1.1Mhat	abnormal cerebral cortex morphology	J:220151
	abnormal cortical marginal zone morphology	J:220151
	abnormal dentate gyrus morphology	J:220151
	abnormal hippocampus CA1 region morphology	J:220151
	abnormal hippocampus morphology	J:220151
	normal behavior/neurological phenotype	J:220151
	normal nervous system phenotype	J:220151

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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