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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Fosl2
fos-like antigen 2
MGI:102858
41 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Col1a1tm2(tetO-Fosl2,-DsRed)Wag/Col1a1+
Tg(Cebpb-tTA)5Bjd/0
involves: 129S4/SvJae * C57BL/6 * NMRI
decreased liver triglyceride level J:210545
decreased susceptibility to diet-induced hepatic steatosis J:210545
normal homeostasis/metabolism phenotype J:213764
Col1a1tm2(tetO-Fosl2,-DsRed)Wag/Col1a1+
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129S4/SvJae * C57BL/6 * CD-1
abnormal osteoblast morphology J:211215
abnormal osteoblast physiology J:211215
abnormal osteoclast morphology J:211215
normal adipose tissue phenotype J:211215
decreased body weight J:211215
decreased circulating adiponectin level J:211215
decreased circulating glucose level J:211215
decreased circulating insulin level J:211215
decreased gonadal fat pad weight J:211215
decreased insulin secretion J:211215
improved glucose tolerance J:211215
increased bone ossification J:211215
increased bone trabecula number J:211215
increased bone volume J:211215
increased circulating osteocalcin level J:211215
increased insulin sensitivity J:211215
increased trabecular bone thickness J:211215
Col1a1tm4(tetO-Jun/Fosl2)Wag/Col1a1+
Tg(Cebpb-tTA)5Bjd/0
involves: 129S4/SvJae * C57BL/6 * NMRI
decreased liver triglyceride level J:210545
decreased susceptibility to diet-induced hepatic steatosis J:210545
Tg(Acta2-cre/ERT2)#Pcn/0
Tgfbr2tm1Karl/Tgfbr2tm1Karl
Tg(H2-K-Fosl2,-EGFP)13Wag/0
B6.Cg-Tgfbr2tm1Karl Tg(Acta2-cre/ERT2)#Pcn Tg(H2-K-Fosl2,-EGFP)13Wag
normal cardiovascular system phenotype J:238723
lung inflammation J:238723
pulmonary fibrosis J:238723
Tg(H2-K-Fosl2,-EGFP)13Wag/0
B6.Cg-Tg(H2-K-Fosl2,-EGFP)13Wag
abnormal lung vasculature morphology J:238723
lung inflammation J:238723
pulmonary fibrosis J:238723
vascular smooth muscle hyperplasia J:238723
Tg(H2-K-Fosl2,-EGFP)13Wag/0
either: 129.Cg-Tg(H2-K-Fosl2,-EGFP)13Wag or B6.Cg-Tg(H2-K-Fosl2,-EGFP)13Wag
abnormal lung morphology J:139032
abnormal pulmonary artery morphology J:139032
cardiac fibrosis J:139032
esophagus fibrosis J:139032
hunched posture J:139032
increased bone mass J:139032
increased fibrosarcoma incidence J:139032
increased lung weight J:139032
liver fibrosis J:139032
premature death J:139032
pulmonary fibrosis J:139032
normal renal/urinary system phenotype J:139032
respiratory distress J:139032
skin fibrosis J:139032
stomach fibrosis J:139032
tachypnea J:139032
thymus fibrosis J:139032

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory