Elk4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Elk4
ELK4, member of ETS oncogene family
MGI:102853

32 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Elk4^{tm1a(EUCOMM)Wtsi}/Elk4⁺ C57BL/6N-Elk4^{tm1a(EUCOMM)Wtsi}/H	decreased body weight	J:165965
Elk4^{tm1a(EUCOMM)Wtsi}/Elk4^{tm1a(EUCOMM)Wtsi} C57BL/6N-Elk4^{tm1a(EUCOMM)Wtsi}/H	abnormal bone mineralization	J:165965
	abnormal bone structure	J:165965
	abnormal cornea morphology	J:165965
	abnormal retina morphology	J:165965
	abnormal tail movements	J:165965
	corneal opacity	J:165965
	decreased body weight	J:165965
	decreased bone mineral density	J:165965
	decreased CD4-positive, alpha-beta T cell number	J:165965
	decreased CD8-positive, alpha-beta T cell number	J:165965
	decreased circulating cholesterol level	J:165965
	decreased circulating HDL cholesterol level	J:165965
	decreased circulating serum albumin level	J:165965
	decreased circulating total protein level	J:165965
	decreased circulating triglyceride level	J:165965
	decreased lean body mass	J:165965
	decreased mature B cell number	J:165965
	decreased T cell number	J:165965
	increased B cell number	J:165965
	increased circulating alkaline phosphatase level	J:165965
	increased lactate dehydrogenase level	J:165965
	increased T cell number	J:165965
Elk4^{tm1a(EUCOMM)Wtsi}/Elk4^{tm1a(EUCOMM)Wtsi} Not Specified	decreased circulating chloride level	J:165965
	decreased circulating fructosamine level	J:165965
	decreased circulating glycerol level	J:165965
	decreased circulating serum albumin level	J:165965
	decreased circulating sodium level	J:165965
	decreased erythrocyte cell number	J:165965
	decreased hematocrit	J:165965
Elk4^tm1Rtr/Elk4^tm1Rtr either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)	abnormal positive T cell selection	J:88515
	abnormal T cell selection	J:88515
	decreased CD4-positive, alpha-beta T cell number	J:88515
	decreased CD8-positive, alpha-beta T cell number	J:88515
	decreased single-positive T cell number	J:88515
	decreased T cell number	J:88515
	decreased thymocyte number	J:88515

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23