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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Acvr2a
activin receptor IIA
MGI:102806
38 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Acvr2atm1.1(KOMP)Vlcg/Acvr2a+
C57BL/6N-Acvr2atm1.1(KOMP)Vlcg/Ucd
abnormal behavior J:211773
decreased eosinophil cell number J:211773
decreased neutrophil cell number J:211773
increased thigmotaxis J:211773
Acvr2atm1.1(KOMP)Vlcg/Acvr2atm1.1(KOMP)Vlcg
C57BL/6N-Acvr2atm1.1(KOMP)Vlcg/Ucd
abnormal craniofacial morphology J:211773
abnormal embryo size J:211773
anophthalmia J:211773
microphthalmia J:211773
preweaning lethality, incomplete penetrance J:211773
Acvr2atm1Hsch/Acvr2atm1Hsch
involves: 129S1/Sv * C57BL/6J
abnormal gastrulation J:57262
abnormal testis development J:57262
cyclopia J:57262
embryonic lethality during organogenesis, incomplete penetrance J:57262
mandible hypoplasia J:57262
reduced female fertility J:57262
Acvr2atm1Zuk/Acvr2atm1Zuk
either: 129 or (involves: 129S7/SvEvBrd * C57BL/6)
abnormal craniofacial bone morphology J:23924
abnormal estrous cycle J:23924
abnormal eyelid morphology J:23924
abnormal ovary morphology J:23924
abnormal seminiferous tubule morphology J:23924
absent corpus luteum J:23924
absent incisors J:23924
azoospermia J:23924
cleft palate J:23924
delayed male fertility J:23924
normal endocrine/exocrine gland phenotype J:23924
female infertility J:23924
increased atretic ovarian follicle number J:23924
mandible hypoplasia J:23924
neonatal lethality, complete penetrance J:23924
normal reproductive system phenotype J:23924
small testis J:23924
suppressed circulating follicle stimulating hormone level J:23924
thin uterus J:23924
Acvr2atm1Zuk/Acvr2atm1Zuk
involves: 129S7/SvEvBrd
abnormal Sertoli cell morphology J:71932
abnormal spermatid morphology J:71932
abnormal spermatogonia morphology J:71932
decreased male germ cell number J:71932
decreased testis weight J:71932

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory