About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ednrb
endothelin receptor type B
MGI:102720
100 phenotypes from 46 alleles in 21 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Ednrbs+Ms/Ednrbs+Ms
JF1/Ms-Ednrbs+Ms/Ms
normal pigmentation phenotype J:199278
Ednrbs-1Acrg/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-1Acrg/Ednrbs-1Acrg
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:16291, J:100221
Ednrbs-1Acrg/Ednrbs-9ThW
involves: 101/Rl * C3H/Rl * C57BL/6J
abnormal diaphragm morphology J:87686
abnormal neuromuscular synapse morphology J:87686
abnormal phrenic nerve morphology J:87686
respiratory distress J:87686
Ednrbs-1Acrg/Ednrbs-48UThc
involves: 101/Rl * C3H/Rl * C57BL/6J
normal muscle phenotype J:87686
normal nervous system phenotype J:87686
normal respiratory system phenotype J:87686
Ednrbs-1Chlc/Ednrbs-1Chlc
involves: 101/Rl * C3H/Rl
megacolon J:10322, J:44601, J:100221
postnatal lethality, incomplete penetrance J:10322, J:16291, J:44601, J:100221
white spotting J:10322, J:16291, J:44601, J:100221
Ednrbs-1MLPf/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-1MLPf/Ednrbs-1MLPf
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:24557, J:100221
Ednrbs-1Pu/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-1Pu/Ednrbs-1Pu
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-1XMLP/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-1XMLP/Ednrbs-1XMLP
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-1XMLPc/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-1XMLPc/Ednrbs-1XMLPc
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-2Btlr/Ednrbs-2Btlr
C57BL/6J-Ednrbs-2Btlr
lethality at weaning J:215823
variable body spotting J:215823
Ednrbs-2CHLd/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-2CHLd/Ednrbs-2CHLd
involves: 101/Rl * C3H/Rl
preweaning lethality, complete penetrance J:10322, J:100221
Ednrbs-2Etopc/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-2Etopc/Ednrbs-2Etopc
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-2MLPl/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-2MLPl/Ednrbs-2MLPl
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-3CHLo/Ednrbs-3CHLo
involves: 101/Rl * C3H/Rl
megacolon J:44601, J:100221
postnatal lethality, complete penetrance J:44601, J:100221
white spotting J:44601, J:100221
Ednrbs-3Etopf/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-3Etopf/Ednrbs-3Etopf
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-4Blec/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-4Blec/Ednrbs-4Blec
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-4Chlc/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-4Chlc/Ednrbs-4Chlc
involves: 101/Rl * C3H/Rl
preweaning lethality, complete penetrance J:10322, J:16291, J:100221
Ednrbs-4Pub/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-4Pub/Ednrbs-4Pub
involves: 101/Rl * C3H/Rl
preweaning lethality, complete penetrance J:16291, J:100221
Ednrbs-9ThW/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-9ThW/Ednrbs-9ThW
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-12MNURn/Ednrbs-12MNURn
involves: 101/Rl * C3H/Rl
postnatal lethality, complete penetrance J:100221
white spotting J:100221
Ednrbs-13Pub/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-13Pub/Ednrbs-13Pub
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-15DttMb/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-15DttMb/Ednrbs-15DttMb
involves: 101/Rl * C3H/Rl
abnormal brain morphology J:125702
abnormal nervous system morphology J:100221, J:125702
abnormal skeleton morphology J:100221
neonatal lethality, complete penetrance J:16291, J:100221
Ednrbs-15DttMb/Ednrbs-15DttMb
involves: 101/Rl * C3H/Rl * C57BL/6J
abnormal diaphragm morphology J:87686
abnormal phrenic nerve morphology J:87686
Ednrbs-15DttMb/Ednrbs
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs-17FrS/Ednrbs-17FrS
involves: 101/Rl * C3H/Rl
megacolon J:44601, J:100221
postnatal lethality, complete penetrance J:44601, J:100221
white spotting J:44601, J:100221
Ednrbs-17Pub/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-17Pub/Ednrbs-17Pub
involves: 101/Rl * C3H/Rl
preweaning lethality, complete penetrance J:16291, J:100221
Ednrbs-24Pub/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-24Pub/Ednrbs-24Pub
involves: 101/Rl * C3H/Rl
preweaning lethality, complete penetrance J:16291, J:100221
Ednrbs-27Pu/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-27Pu/Ednrbs-27Pu
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-27Pub/Ednrbs-27Pub
involves: 101/Rl * C3H/Rl
megacolon J:44601, J:100221
postnatal lethality, complete penetrance J:16291, J:44601, J:100221
white spotting J:16291, J:44601, J:100221
Ednrbs-29Pub/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-29Pub/Ednrbs-29Pub
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-31Pub/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-31Pub/Ednrbs-31Pub
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-36Pub/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-36Pub/Ednrbs-36Pub
B6.Cg-Ednrbs-36Pub
abnormal bone ossification J:125229
abnormal palatal rugae morphology J:125229
abnormal secondary palate development J:125229
abnormal soft palate morphology J:125229
absent palatine bone horizontal plate J:125229
cleft secondary palate J:125229
cleft upper lip J:125229
failure of palatal shelf elevation J:125229
increased cell proliferation J:125229
increased mitotic index J:125229
maxillary shelf hypoplasia J:125229
Ednrbs-36Pub/Ednrbs-36Pub
involves: 101/Rl * C3H/Rl
abnormal cartilage morphology J:100221
abnormal nervous system morphology J:100221
abnormal skeleton morphology J:100221
neonatal lethality, complete penetrance J:16291, J:100221
Ednrbs-48UThc/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-48UThc/Ednrbs-48UThc
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-52Pub/Ednrb+
involves: 101/Rl * C3H/Rl
decreased body size J:100221
Ednrbs-52Pub/Ednrbs-52Pub
involves: 101/Rl * C3H/Rl
prenatal lethality, complete penetrance J:100221
Ednrbs-136H/Ednrbs-136H
involves: 101/H * C3H/HeH
belly spot J:180879
head spot J:180879
white spotting J:180879
Ednrbs-160H/Ednrbs-160H
involves: C3H/HeH
white spotting J:181531
Ednrbs-161H/Ednrbs-161H
involves: C3H/HeH
white spotting J:181531
Ednrbs-162H/Ednrbs-162H
involves: C3H/HeH
decreased body size J:180879
white spotting J:180879, J:181531
Ednrbs-Btlr/Ednrbs-Btlr
C57BL/6J-Ednrbs-Btlr
lethality at weaning, complete penetrance J:202015
variable body spotting J:202015
Ednrbs-l/Ednrbs-l
involves: C3H/HeJ * C57BL/6
abnormal coat/hair pigmentation J:5008
abnormal cochlear hair cell morphology J:5048
abnormal cochlear sensory epithelium morphology J:5048
abnormal Deiters cell morphology J:5048
abnormal enteric nervous system morphology J:5008
abnormal hindgut morphology J:5407
abnormal inner ear morphology J:5048
abnormal pigmentation pattern J:5008
abnormal stria vascularis morphology J:5048
absent enteric neurons J:5008
megacolon J:5008
postnatal lethality J:5008
premature death J:5008
preweaning lethality, incomplete penetrance J:5008
Ednrbs-l/Ednrbs-l
involves: C57BL/6J * SSL/Le
abnormal coat/hair pigmentation J:19441
abnormal melanocyte proliferation J:19441
abnormal pigmentation pattern J:19441
Ednrbs/Ednrbs-1Acrg
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-1Chlc
involves: 101/Rl * C3H/Rl
white spotting J:100221
Ednrbs/Ednrbs-1MLPf
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-1Pu
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-1XMLP
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-1XMLPc
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-2CHLd
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-2Etopc
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-2MLPl
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-3CHLo
involves: 101/Rl * C3H/Rl
white spotting J:100221
Ednrbs/Ednrbs-3Etopf
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-4Blec
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-4Chlc
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-4Pub
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-9ThW
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-12MNURn
involves: 101/Rl * C3H/Rl
white spotting J:100221
Ednrbs/Ednrbs-13Pub
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-17FrS
involves: 101/Rl * C3H/Rl
white spotting J:100221
Ednrbs/Ednrbs-17Pub
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-24Pub
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-27Pu
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-27Pub
involves: 101/Rl * C3H/Rl
white spotting J:100221
Ednrbs/Ednrbs-29Pub
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-31Pub
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-36Pub
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-48UThc
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs-52Pub
involves: 101/Rl * C3H/Rl
decreased body size J:100221
white spotting J:100221
Ednrbs/Ednrbs
Not Specified
abnormal foot pigmentation J:30758
abnormal tail pigmentation J:30758
megacolon J:15014
variable body spotting J:12952, J:30758
variable depigmentation J:30758
white spotting J:12952
Ednrbtm1(tTA)Tilg/Ednrbtm3(tetO)Tilg
involves: 129P2/OlaHsd * 129S1/Sv
abnormal enteric neuron morphology J:58698
absent coat pigmentation J:58698
normal digestive/alimentary phenotype J:58698
megacolon J:58698
normal pigmentation phenotype J:58698
Ednrbtm1.1Nrd/Ednrb+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal blood pH regulation J:226561
abnormal oxygen level J:226561
decreased circulating lactate level J:226561
decreased response of heart to induced stress J:226561
hypocapnia J:226561
increased cardiac muscle contractility J:226561
increased cardiac output J:226561
increased mean systemic arterial blood pressure J:226561
Ednrbtm1.1Nrd/Ednrbtm1.1Nrd
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal coat/hair pigmentation J:226561
cachexia J:226561
decreased body size J:226561
lethality at weaning, complete penetrance J:226561
megacolon J:226561
white spotting J:226561
Ednrbtm1.1Yko/Ednrbtm1.1Yko
involves: 129P2/OlaHsd * Bkl:BKW * C57BL/6 * SJL
decreased vasodilation J:135711
intestinal obstruction J:135711
postnatal lethality, complete penetrance J:135711
white spotting J:135711
Ednrbtm1Myks/Ednrbtm1Myks
involves: 129P2/OlaHsd
abnormal cell migration J:84057
absent coat pigmentation J:84057
megacolon J:84057
premature death J:84057
Ednrbtm1Yko/Ednrbtm1Yko
Tg(AQP2-cre)2Dek/0
involves: C57BL/6 * CBA
abnormal urine homeostasis J:116002
abnormal urine sodium level J:116002
decreased renin activity J:116002
increased systemic arterial blood pressure J:116002
increased systemic arterial diastolic blood pressure J:116002
increased systemic arterial systolic blood pressure J:116002
oliguria J:116002
Ednrbtm1Yko/Ednrbtm1Yko
Tg(Tek-cre)1Ywa/0
involves: 129P2/OlaHsd * Bkl:BKW * C57BL/6 * SJL
abnormal blood homeostasis J:135711
abnormal nitric oxide homeostasis J:135711
normal cardiovascular system phenotype J:135711
decreased vasodilation J:135711
Ednrbtm1Ywa/Ednrb+
involves: 129S/SvEvBrd
decreased acute inflammation J:103977
hypoalgesia J:103977
Ednrbtm1Ywa/Ednrbs
involves: 129S/SvEv
abnormal blood gas level J:60070
hypercapnia J:60070
hypoxia J:60070
increased mean systemic arterial blood pressure J:60070
Ednrbtm1Ywa/Ednrbtm1Ywa
B6;129-Ednrbtm1Ywa/J
abnormal colon goblet cell morphology J:216833
abnormal colon morphology J:216833
abnormal feces composition J:216833
abnormal intestinal mucosa morphology J:216833
abnormal intestine physiology J:216833
abnormal large intestine crypts of Lieberkuhn morphology J:216833
Ednrbtm1Ywa/Ednrbtm1Ywa
involves: 129S5/SvEvBrd
abnormal choroid pigmentation J:22206
abnormal coat/hair pigmentation J:22206
abnormal hair follicle melanocyte morphology J:22206
aganglionic megacolon J:22206
cachexia J:22206
decreased acute inflammation J:103977
hypoalgesia J:103977
intestinal obstruction J:22206
postnatal growth retardation J:22206
premature death J:22206
variable depigmentation J:22206
white spotting J:22206
Ednrbtm2(rtTA)Tilg/Ednrbtm3(tetO)Tilg
involves: 129P2/OlaHsd * 129S1/Sv
abnormal enteric neuron morphology J:58698
absent coat pigmentation J:58698
normal digestive/alimentary phenotype J:58698
megacolon J:58698
normal pigmentation phenotype J:58698
premature death J:58698
EdnrbWS4/EdnrbWS4
involves: BALB/c * MSM
abnormal cochlea morphology J:76584
abnormal hearing physiology J:76584
abnormal stria vascularis morphology J:76584
absent strial intermediate cells J:76584
cochlear hair cell degeneration J:76584
deafness J:76584
megacolon J:76584
organ of Corti degeneration J:76584
premature death J:76584
thin stria vascularis J:76584
variable body spotting J:76584

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/14/2017
MGI 6.11
The Jackson Laboratory