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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cav1
caveolin 1, caveolae protein
MGI:102709
31 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Apoetm1Unc/Apoetm1Unc
Cav1tm1Mls/Cav1tm1Mls
involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * SJL
decreased susceptibility to atherosclerosis J:101788
increased circulating cholesterol level J:101788
increased circulating LDL cholesterol level J:101788
increased circulating triglyceride level J:101788
increased circulating VLDL cholesterol level J:101788
Cav1tm1.1Aia/Cav1tm1.1Aia
crsp/+
involves: 129S7/SvEvBrd * C57BL/6J * FVB
enlarged endometrial glands J:174719
increased endometrial gland number J:174719
normal neoplasm J:174719
ovary cysts J:174719
normal reproductive system phenotype J:174719
uterus cysts J:174719
Cav1tm1.1Aia/Cav1tm1.1Aia
crsp/crsp
involves: 129S7/SvEvBrd * C57BL/6J * FVB
enlarged endometrial glands J:174719
increased endometrial gland number J:174719
normal neoplasm J:174719
ovary cysts J:174719
uterus cysts J:174719
Cav1tm1.1Aia/Cav1tm1.1Aia
Rxfp2tm1Aia/Rxfp2+
involves: 129S7/SvEvBrd * C57BL/6J * FVB
abnormal uterus physiology J:174719
enlarged endometrial glands J:174719
increased endometrial gland number J:174719
normal neoplasm J:174719
ovary cysts J:174719
normal reproductive system phenotype J:174719
uterus cysts J:174719
Cav1tm1Mls/Cav1+
Tg(MMTV-PyVT)634Mul/0
involves: 129/Sv * C57BL/6J * FVB/N * SJL
increased mammary gland tumor incidence J:132472
Cav1tm1Mls/Cav1tm1Mls
Cav3tm1Mls/Cav3tm1Mls
involves: 129/Sv * C57BL/6J * SJL
abnormal myocardial fiber morphology J:77372
absent caveolae J:77372
cardiac hypertrophy J:77372
cardiac interstitial fibrosis J:77372
cardiomyopathy J:77372
decreased ventricle muscle contractility J:77372
dilated heart left ventricle J:77372
heart inflammation J:77372
heart left ventricle hypertrophy J:77372
increased heart weight J:77372
thick interventricular septum J:77372
thick ventricular wall J:77372
Cav1tm1Mls/Cav1tm1Mls
Cdkn2atm1Rdp/Cdkn2atm1Rdp
involves: 129/Sv * C57BL/6 * SJL
abnormal branching of the mammary ductal tree J:90334
abnormal cell cycle J:90334
abnormal mammary gland duct morphology J:90334
increased fibroblast proliferation J:90334
mammary gland duct hyperplasia J:90334
Cav1tm1Mls/Cav1tm1Mls
Tg(MMTV-PyVT)634Mul/0
involves: 129/Sv * C57BL/6J * FVB/N * SJL
increased mammary gland tumor incidence J:132472
Cav1tm1Mls/Cav1tm1Mls
Tg(TRAMP)8247Ng/0
involves: 129/Sv * C57BL/6 * SJL
decreased tumor incidence J:133066

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory