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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Efnb1
ephrin B1
MGI:102708
26 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Efnb1tm1.1Jwu/Efnb1tm1.1Jwu
Efnb2tm1.1Jwu/Efnb2tm1.1Jwu
Tg(Lck-cre)I540Jxm/0
B6.Cg-Efnb2tm1.1Jwu Efnb1tm1.1Jwu Tg(Lck-cre)I540Jxm
abnormal bone marrow cell morphology/development J:178148
abnormal T cell differentiation J:178148
abnormal T-helper 1 cell differentiation J:178148
abnormal T-helper 17 cell differentiation J:178148
decreased CD4-positive, alpha-beta T cell number J:178148
decreased CD8-positive, alpha-beta T cell number J:178148
decreased DN4 thymocyte number J:178148
decreased double-positive T cell number J:178148
decreased spleen weight J:178148
decreased T cell number J:178148
decreased thymus weight J:178148
increased DN3 thymocyte number J:178148
increased double-negative T cell number J:178148
increased length of allograft survival J:178148
increased susceptibility to Riboviria infection J:178148
increased thymocyte apoptosis J:178148
small spleen J:178148
small thymus J:178148
spleen hypoplasia J:178148
thymus hypoplasia J:178148
Efnb1tm1.1Sor/Efnb1+
Efnb2tm2Sor/Efnb2+
involves: 129S4/SvJaeSor * C57BL/6J
abnormal tracheal cartilage morphology J:143845
failure of eyelid fusion J:143845
small salivary gland J:143845
Efnb1tm1.1Sor/Efnb1+
Efnb2tm2Sor/Efnb2tm2Sor
involves: 129S4/SvJaeSor * C57BL/6
abnormal coronal suture morphology J:115952
abnormal frontal bone morphology J:115952
Efnb1tm1.1Sor/Y
Efnb2tm2Sor/Efnb2+
involves: 129S4/SvJaeSor * C57BL/6J
abnormal tracheal cartilage morphology J:143845
failure of eyelid fusion J:143845
small salivary gland J:143845
Efnb1tm1.1Sor/Y
Efnb2tm2Sor/Efnb2tm2Sor
involves: 129S4/SvJaeSor * C57BL/6
normal craniofacial phenotype J:115952

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory