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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tbx6
T-box 6
MGI:102539
19 phenotypes from 6 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tbx6dd1/Tbx6dd1
involves: C3HeB/FeJ * C57BL/6J 		abnormal neural tube morphology J:98216
abnormal paraxial mesoderm morphology J:98216
Tbx6em1Fzh/Tbx6+
FVB/NJ-Tbx6em1Fzh 		normal skeleton phenotype J:271649
Tbx6em1Fzh/Tbx6em1Fzh
FVB/NJ-Tbx6em1Fzh 		prenatal lethality, complete penetrance J:271649
Tbx6em1Fzh/Tbx6em2Fzh
FVB/NJ-Tbx6em1Fzh Tbx6em2Fzh 		abnormal vertebrae development J:271649
rib fusion J:271649
vertebral fusion J:271649
Tbx6em2Fzh/Tbx6em2Fzh
FVB/NJ-Tbx6em2Fzh 		normal skeleton phenotype J:271649
Tbx6em3Fzh/Tbx6em3Fzh
C57BL/6J-Tbx6em3Fzh 		abnormal vertebrae morphology J:288810
vertebral fusion J:288810
Tbx6tm1Pa/Tbx6tm1Pa
involves: 129S1/Sv * 129X1/SvJ 		abnormal mesoderm development J:217059
abnormal neural tube morphology J:217059
Tbx6tm1Pa/Tbx6tm1Pa
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal intersomitic artery morphology J:80954
abnormal paraxial mesoderm morphology J:80954
abnormal vascular development J:80954
embryonic lethality during organogenesis, complete penetrance J:80954
enlarged tail bud J:80954
hematoma J:80954
impaired somite development J:80954
kinked neural tube J:80954
Tbx6tm1Pa/Tbx6tm2Pa
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR 		abnormal direction of embryo turning J:137163
abnormal direction of heart looping J:137163
abnormal motile primary cilium morphology J:137163
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory