F2rl1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

F2rl1
F2R like trypsin receptor 1
MGI:101910

24 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
F2r^tm1.1Cgh/F2r^tm1.1Cgh F2rl1^tm2Cgh/F2rl1^tm2Cgh Tg(Tek-F2r)1Cgh/0 involves: 129S4/SvJae * C57BL/6	normal cardiovascular system phenotype	J:157446
	exencephaly	J:157446
	normal mortality/aging	J:157446
F2r^tm1Ajc/F2r^tm1Ajc F2rl1^tm1Cgh/F2rl1^tm1Cgh involves: 129S4/SvJae	abnormal neural tube morphology	J:188121
	curly tail	J:188121
	spina bifida	J:188121
F2r^tm1Ajc/F2r^tm1Ajc F2rl1^tm1Cgh/F2rl1^tm1Cgh involves: 129S4/SvJae * C57BL/6	decreased survivor rate	J:132733
	embryonic lethality, incomplete penetrance	J:132733
	increased susceptibility to endotoxin shock	J:132733
	increased susceptibility to induced morbidity/mortality	J:132733
F2r^tm1Ajc/F2r^tm1Ajc F2rl1^tm1Cgh/F2rl1^tm1Cgh F2rl3^tm1Cgh/F2rl3^tm1Cgh involves: 129S4/SvJae * C57BL/6	embryonic lethality	J:132733
F2r^tm2Cgh/F2r⁺ F2rl1^tm2Cgh/F2rl1⁺ involves: 129S4/SvJae * C57BL/6	incomplete rostral neuropore closure	J:157446
F2rl1^tm1Bpd/F2rl1^tm1Bpd F3^tm1.1Dwr/F3^tm1.1Dwr B6.129-F3^tm1.1Dwr F2rl1^tm1Bpd	normal cardiovascular system phenotype	J:135087
F2rl1^tm1Bpd/F2rl1^tm1Bpd Tg(MMTV-PyVT)634Mul/0 B6.Cg-F2rl1^tm1Bpd Tg(MMTV-PyVT)634Mul	abnormal tumor vascularization	J:138924
	decreased mammary gland tumor incidence	J:138924
	increased adenoma incidence	J:138924
	increased mammary adenocarcinoma incidence	J:138924
F2rl1^tm1Cgh/F2rl1^tm1Cgh Spink5^tm1Hov/Spink5^tm1Hov involves: 129P2/OlaHsd * 129S4/SvJae	abnormal epidermis stratum corneum morphology	J:180855
	abnormal skin morphology	J:180855
	abnormal vibrissa morphology	J:180855
	acanthosis	J:180855
	dehydration	J:180855
	neonatal lethality, complete penetrance	J:180855
F2rl1^tm1Cgh/F2rl1^tm1Cgh Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} involves: 129P2/OlaHsd * 129S4/SvJae	embryonic lethality, complete penetrance	J:188121
F2rl1^tm1Cgh/F2rl1^tm1Cgh Spint2^{Gt(KST272)Byg}/Spint2^{Gt(KST272)Byg} St14^tm1Bug/St14⁺ involves: 129P2/OlaHsd * 129S4/SvJae	exencephaly	J:188121
F2rl1^tm1Cgh/F2rl1^tm1Cgh Tg(KRT14-Prss8)2Hum/? involves: 129S4/SvJae * C57BL/6 * DBA/2	normal integument phenotype	J:189278

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23