121 phenotypes from 7 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mmp14m1Btlr/Mmp14m1Btlr C57BL/6J-Mmp14m1Btlr	abnormal postnatal growth/weight/body size	J:133626
	decreased body weight	J:133626
	decreased cranium height	J:133626
	infertility	J:133626
	macrophthalmia	J:133626
	premature death	J:133626
	prenatal lethality, incomplete penetrance	J:133626
	short snout	J:133626
Mmp14sabe/Mmp14sabe B6(129P2)-Mmp14sabe/GrsrJ	abnormal gait	J:127164
	decreased body size	J:127164
	decreased cranium height	J:127164
	decreased cranium width	J:127164
	domed cranium	J:127164
	enlarged optic nerve	J:127164
	exophthalmos	J:127164
	increased or absent threshold for auditory brainstem response	J:127164
	increased percent body fat/body weight	J:127164
	premature death	J:127164
	round head	J:127164
	short mandible	J:127164
	short maxilla	J:127164
	small ears	J:127164
	normal vision/eye phenotype	J:127164
Mmp14tm1Hbh/Mmp14tm1Hbh involves: 129P1/ReJ * 129P2/OlaHsd * Black Swiss	abnormal club cell morphology	J:97067
	abnormal pulmonary alveolus morphology	J:97067
	abnormal pulmonary elastic fiber morphology	J:97067
	abnormal terminal bronchiole morphology	J:97067
	absent alveolar pores	J:97067
	dilated pulmonary alveolar duct	J:97067
	dilated respiratory conducting tube	J:97067
	impaired lung alveolus development	J:97067
	overexpanded pulmonary alveolus	J:97067
	pulmonary hypoplasia	J:97067
Mmp14tm1Hbh/Mmp14tm1Hbh involves: 129P2/OlaHsd	abnormal chondrocyte morphology	J:130212
	decreased cranium length	J:130212
	short humerus	J:130212
Mmp14tm1Hbh/Mmp14tm1Hbh involves: 129P2/OlaHsd * Black Swiss	abnormal bone ossification	J:57969
	abnormal bone remodeling	J:86538
	abnormal cartilage development	J:86538
	abnormal cartilage morphology	J:57969
	abnormal chondrocyte morphology	J:57969, J:86538
	abnormal cranial suture morphology	J:57969
	abnormal cranium morphology	J:57969
	abnormal fontanelle morphology	J:57969
	abnormal forelimb morphology	J:57969
	abnormal interparietal bone morphology	J:57969
	abnormal joint morphology	J:86538
	abnormal long bone epiphyseal plate morphology	J:57969
	abnormal long bone morphology	J:57969
	abnormal Meckel's cartilage morphology	J:86538
	abnormal neurocranium morphology	J:57969
	abnormal orbit morphology	J:57969
	abnormal osteoclast physiology	J:57969, J:86538
	abnormal parietal bone morphology	J:57969, J:86538
	abnormal skeleton development	J:57969, J:198679
	abnormal skeleton physiology	J:57969
	abnormal trabecular bone morphology	J:57969
	absent sexual maturation	J:57969
	arthritis	J:57969
	cachexia	J:57969
	decreased body size	J:57969
	decreased body weight	J:57969
	decreased bone mineral density	J:57969
	decreased length of long bones	J:57969
	decreased locomotor activity	J:57969
	delayed bone ossification	J:57969
	disproportionate dwarf	J:57969
	domed cranium	J:57969
	focal hair loss	J:57969
	impaired osteoblast differentiation	J:198679
	kyphosis	J:57969
	lordosis	J:57969
	osteoporosis	J:57969
	postnatal lethality, incomplete penetrance	J:57969
	premature death	J:57969
	short snout	J:57969
	skeletal muscle fibrosis	J:57969
	skin fibrosis	J:57969
Mmp14tm1Ktry/Mmp14tm1Ktry B6.129X1-Mmp14tm1Ktry	abnormal axial skeleton morphology	J:61685
	abnormal bone mineralization	J:61685
	abnormal bone ossification	J:61685
	abnormal cartilage development	J:61685
	abnormal cranial suture morphology	J:61685
	abnormal cranial vertex morphology	J:61685
	abnormal craniofacial morphology	J:61685
	abnormal cranium morphology	J:61685
	abnormal long bone epiphyseal plate proliferative zone	J:61685
	abnormal neurocranium morphology	J:61685
	abnormal upper incisor morphology	J:61685
	cachexia	J:61685
	decreased angiogenesis	J:61685
	decreased body weight	J:61685
	decreased locomotor activity	J:61685
	delayed endochondral bone ossification	J:61685
	domed cranium	J:61685
	increased width of hypertrophic chondrocyte zone	J:61685
	lethality at weaning, complete penetrance	J:61685
	loose skin	J:61685
	malocclusion	J:61685
	short incisors	J:61685
	short limbs	J:61685
	short lower incisors	J:61685
	short mandible	J:61685
	short maxilla	J:61685
	short snout	J:61685
	short upper incisors	J:61685
	small cranial cavity	J:61685
Mmp14tm1Ktry/Mmp14tm1Ktry involves: 129X1/SvJ	abnormal dendritic cell physiology	J:138782
	abnormal incisor morphology	J:103089
	abnormal tooth development	J:103089
	delayed tooth eruption	J:103089
	small mandible	J:103089
Mmp14tm1Ktry/Mmp14tm1Ktry involves: 129X1/SvJ * C57BL/6	abnormal bronchiole morphology	J:95881
	abnormal lung morphology	J:95881
	abnormal pulmonary alveolus morphology	J:95881
	abnormal submandibular gland branching morphogenesis	J:95881
	decreased submandibular gland size	J:95881
	overexpanded pulmonary alveolus	J:95881
	postnatal lethality, complete penetrance	J:95881
	small lung	J:95881
Mmp14tm1Noda/Mmp14tm1Noda Not Specified	no abnormal phenotype detected	J:91198
Mmp14tm1Ski/Mmp14tm1Ski B6.Cg-Mmp14tm1Ski	abnormal basement membrane morphology	J:165029
	abnormal joint morphology	J:113113
	abnormal kidney corticomedullary boundary morphology	J:165029
	abnormal kidney development	J:165029
	abnormal kidney morphology	J:165029
	abnormal kidney papilla morphology	J:165029
	abnormal skeletal muscle fiber morphology	J:113113, J:165029
	abnormal skeleton physiology	J:113113
	centrally nucleated skeletal muscle fibers	J:113113
	decreased body size	J:165029
	decreased kidney cell proliferation	J:165029
	decreased renal glomerulus number	J:165029
	impaired branching involved in ureteric bud morphogenesis	J:165029
	increased skeletal muscle fiber size	J:113113
	kidney cortex hypoplasia	J:165029
	postnatal lethality	J:165029
	premature death	J:113113
	skeletal muscle interstitial fibrosis	J:113113
	small kidney	J:165029
Mmp14tm1Stjw/Mmp14tm1Stjw Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 involves: C57BL/6 * CD-1	normal adipose tissue phenotype	J:198679
	decreased bone mineral density	J:198679
	delayed cranial suture closure	J:198679
	delayed intramembranous bone ossification	J:198679
	normal skeleton phenotype	J:198679
Mmp14tm1Stjw/Mmp14tm1Stjw Twist2tm1.1(cre)Dor/Twist2+ involves: 129X1/SvJ * C57BL/6	abnormal bone ossification	J:198679
	abnormal cartilage morphology	J:198679
	abnormal hypodermis fat layer morphology	J:198679
	abnormal joint morphology	J:198679
	decreased body size	J:198679
	decreased body weight	J:198679
	decreased bone mineral density	J:198679
	delayed cranial suture closure	J:198679
	delayed intramembranous bone ossification	J:198679
	domed cranium	J:198679
	increased bone marrow adipose tissue amount	J:198679
	postnatal growth retardation	J:198679
	premature death	J:198679
	short snout	J:198679
	normal skeleton phenotype	J:198679