61 phenotypes from 7 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dag1tm1.1Swin/Dag1tm1.1Swin involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:187750
Dag1tm1Kcam/Dag1tm1Kcam involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal embryonic tissue morphology	J:40601
	abnormal extraembryonic tissue morphology	J:40601
	abnormal Reichert's membrane morphology	J:40601
	absent extraembryonic ectoderm	J:40601
	absent mesoderm	J:40601
	decreased embryo size	J:40601
	embryonic growth arrest	J:40601
	embryonic lethality during organogenesis, incomplete penetrance	J:40601
	failure to gastrulate	J:40601
Dag1tm1Kcam/Dag1tm2.1Kcam Edil3Tg(Sox2-cre)1Amc/Edil3+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal axon fasciculation	J:194150
	abnormal axon guidance	J:194150
	abnormal basement membrane morphology	J:194150
	abnormal spinal cord dorsal column morphology	J:194150
	abnormal spinal cord ventral commissure morphology	J:194150
	radial glial endfoot detachment	J:194150
Dag1tm1Kcam/Dag1tm2Kcam Tg(GFAP-cre)25Mes/0 involves: 129S1/Sv * 129X1/SvJ * FVB/N	abnormal neuronal migration	J:86901
	increased brain size	J:86901
	megacephaly	J:86901
Dag1tm2Kcam/Dag1tm2Kcam Myl2tm1(cre)Krc/Myl2+ involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	abnormal cardiac muscle contractility	J:169951
	abnormal heart left ventricle wall thickness	J:169951
	cardiac fibrosis	J:169951
	dilated cardiomyopathy	J:169951
	myocardial fiber degeneration	J:169951
Dag1tm2Kcam/Dag1tm2Kcam Tg(Ckmm-cre)5Khn/0 involves: 129S1/Sv * 129X1/SvJ * FVB	abnormal skeletal muscle morphology	J:78838
	centrally nucleated skeletal muscle fibers	J:78838
	dystrophic muscle	J:78838
	increased body size	J:78838
	increased circulating creatine kinase level	J:78838
	increased skeletal muscle fiber diameter	J:78838
	increased skeletal muscle fiber size	J:78838
	increased skeletal muscle weight	J:78838
	increased variability of skeletal muscle fiber size	J:78838
	skeletal muscle necrosis	J:78838
Dag1tm2Kcam/Dag1tm2Kcam Tg(GFAP-cre)25Mes/0 involves: 129S1/Sv * 129X1/SvJ * FVB/N	abnormal brain morphology	J:86901
	abnormal cerebellar cortex morphology	J:86901
	abnormal cerebellum development	J:86901
	abnormal cerebral cortex morphology	J:86901
	abnormal hippocampus CA1 region morphology	J:86901
	abnormal hippocampus granule cell layer	J:86901
	abnormal neuronal migration	J:86901
	abnormal rod electrophysiology	J:158199
	abnormal stratification in cerebral cortex	J:86901
	abnormal subarachnoid space morphology	J:86901
	astrocytosis	J:86901
	increased brain size	J:86901
	megacephaly	J:86901
	reduced long-term potentiation	J:86901
Dag1tm2Kcam/Dag1tm2Kcam Tg(Mpz-cre)26Mes/0 involves: 129 * C57BL/6 * FVB/N	abnormal action potential	J:137852
	abnormal myelin sheath morphology	J:137852
	abnormal nerve conduction	J:137852
	decreased nerve conduction velocity	J:137852
	demyelination	J:137852
Dag1tm2Kcam/Dag1tm2Kcam Tg(Myh11-cre)5013Gko/0 involves: 129S1/Sv * 129X1/SvJ	normal cardiovascular system phenotype	J:169951
Dag1tm2Kcam/Dag1tm2Kcam Tg(Nes-cre)1Kln/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal rod electrophysiology	J:158199
	anterior iris synechia	J:158199
	blindness	J:158199
	buphthalmos	J:158199
	corneal opacity	J:158199
	microphthalmia	J:158199
	mydriasis	J:158199
Dag1tm2Kcam/Dag1tm2Kcam Tg(Pax3-cre)1Joe/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal neuromuscular synapse morphology	J:142595
Dag1tm3Kcam/Dag1tm3Kcam involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal rod electrophysiology	J:158199
	prenatal lethality, incomplete penetrance	J:158199
Dag1tm4.1Kcam/Dag1tm4.1Kcam involves: 129S1/Sv * 129X1/SvJ	abnormal neuromuscular synapse morphology	J:169291
	normal cardiovascular system phenotype	J:169291
	centrally nucleated skeletal muscle fibers	J:169291
	decreased grip strength	J:169291
	dystrophic muscle	J:169291
	limb grasping	J:169291
Dag1tm5Kcam/Dag1tm5Kcam B6.129S6-Dag1tm5Kcam/J	no abnormal phenotype detected	J:101977