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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
F2r
coagulation factor II thrombin receptor
MGI:101802
63 phenotypes from 4 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
F2rtm1Ajc/F2rtm1Ajc
B6.129S4-F2rtm1Ajc
abnormal bone volume J:217458
abnormal cell physiology J:76348
abnormal circulating protein level J:217458
abnormal neuron apoptosis J:89774
abnormal sinus venosus morphology J:71309
abnormal urine protein level J:217458
abnormal vitelline vasculature morphology J:71309
absent vitelline blood vessels J:71309
decreased bone trabecular spacing J:217458
decreased compact bone thickness J:217458
decreased tumor necrosis factor (ligand) superfamily member 11 level J:217458
distended pericardium J:71309
embryonic growth retardation J:71309
embryonic lethality during organogenesis, incomplete penetrance J:71309
hemopericardium J:71309
hemorrhage J:71309
normal homeostasis/metabolism phenotype J:217458
increased body weight J:217458
increased bone mineral density J:217458
increased bone trabecula number J:217458
increased compact bone volume J:217458
increased trabecular bone volume J:217458
increased tumor necrosis factor receptor superfamily member 11b level J:217458
increased urine pH J:217458
increased urine sodium level J:217458
long femur J:217458
normal neoplasm J:92278
polyuria J:217458
normal skeleton phenotype J:217458
F2rtm1Ajc/F2rtm1Ajc
involves: 129S4/SvJae
curly tail J:188121
embryonic lethality during organogenesis, incomplete penetrance J:33380
F2rtm1Ajc/F2rtm1Ajc
involves: 129S4/SvJae * C57BL/6
abnormal gallbladder physiology J:123689
normal immune system phenotype J:132733
F2rtm1Ajc/F2rtm1Ajc
involves: 129S4/SvJae * C57BL/6J
abnormal cell physiology J:33380
abnormal placenta development J:33380
absent heartbeat J:33380
decreased embryo size J:33380
embryonic growth retardation J:33380
embryonic lethality during organogenesis, incomplete penetrance J:33380
normal hematopoietic system phenotype J:33380
F2rtm1Pago/F2rtm1Pago
B6.129P2-F2rtm1Pago
abnormal heart left ventricle morphology J:142990
abnormal response to cardiac infarction J:142990
normal cardiovascular system phenotype J:135087
normal immune system phenotype J:88245
F2rtm1Pago/F2rtm1Pago
involves: 129P2/OlaHsd
abnormal cytokine level J:133917
abnormal lymph node morphology J:133917
decreased susceptibility to endotoxin shock J:133917
decreased susceptibility to induced morbidity/mortality J:133917
enlarged mesenteric lymph nodes J:133917
F2rtm1Pago/F2rtm1Pago
involves: 129P2/OlaHsd * C57BL/6
abnormal blood pressure regulation J:38032
abnormal carotid artery morphology J:103347
abnormal fertility/fecundity J:38032
abnormal intestine physiology J:96182
abnormal systemic arterial blood pressure J:96312
abnormal systemic arterial blood pressure regulation J:38032
abnormal vascular wound healing J:103347
normal cardiovascular system phenotype J:38032, J:124465
decreased inflammatory response J:124648
decreased susceptibility to induced colitis J:94420
decreased vascular permeability J:124465
embryonic lethality during organogenesis, incomplete penetrance J:38032
F2rtm2Cgh/F2rtm2Cgh
involves: 129S4/SvJae * C57BL/6
abnormal cardiovascular system physiology J:157446
curly tail J:157446
decreased survivor rate J:157446
edema J:157446
exencephaly J:157446
lethality throughout fetal growth and development, incomplete penetrance J:157446
spina bifida J:157446
Tg(Myh6-F2r)18Nmk/0
involves: C57BL/6J
abnormal cardiovascular system physiology J:142990
dilated heart left ventricle J:142990
enlarged heart J:142990
increased heart weight J:142990

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory