About   Help   FAQ
Gng7
Gene Detail
 Symbol
Name
ID
Gng7
guanine nucleotide binding protein (G protein), gamma 7
MGI:95787
Feature Type protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr10:80948624-81014945 bp, - strand
From VEGA annotation of GRCm38

  66322 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31293  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: GTP-binding regulatory protein gamma chain
Gene Tree: Gng7

Human
homologs
Human Homolog GNG7, guanine nucleotide binding protein (G protein), gamma 7
NCBI Gene ID 2788
neXtProt AC  NX_O60262
Human Chr (Location)  19p13.3; chr19:2511220-2702748 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(116) : Gene trapped(108) Targeted(8)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit an enhanced startle response, loss of dopamine- and forskolin-stimulated adenylyl cyclase activity in the striatum, and increased mean insulin levels in males.
 
Phenotype Images(1)
Interactions
Gng7 interacts with 284 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process behavioral fear response, G-protein coupled receptor signaling pathway, ...
Component extracellular vesicular exosome, heterotrimeric G-protein complex, ...
Function signal transducer activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (110)    Tissues (38)    Images (52)
Theiler Stages: 1, 2, 3, 4, 19, 23, 28
Assay TypeResults
RNA in situ 103
RT-PCR 7
cDNA source data(21)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(21) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000030294 (Evidence)
Ensembl Gene ModelENSMUSG00000048240 (Evidence)
Entrez Gene14708 (Evidence)
UniGene222496
DFCITC1585194, TC1604854, TC1626539
DoTSDT.101377940, DT.110603524, DT.40182368
NIA Mouse Gene IndexU032029
Consensus CDS ProjectCCDS24039.1
International Mouse Knockout Project StatusGng7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030294 VEGA Gene Model | MGI Sequence Detail 66322 C57BL/6J ±  kb
transcript OTTMUST00000074996 VEGA | MGI Sequence Detail 3382 Not Applicable 
polypeptide OTTMUSP00000039239 VEGA | MGI Sequence Detail 68 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(6) UniProt(5)
Polymorphisms RFLP(1) : SNPs within 2kb(125 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015898 G-protein gamma-like domain
InterPro IPR001770 G-protein, gamma subunit
Protein Ontology PR:000008111 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
References (Earliest) J:22157 Cali JJ, et al., Selective tissue distribution of G protein gamma subunits, including a new form of the gamma subunits identified by cDNA cloning. J Biol Chem. 1992 Nov 25;267(33):24023-7
(Latest) J:193905 Sasaki K, et al., Age-dependent dystonia in striatal Ggamma7 deficient mice is reversed by the dopamine D2 receptor agonist pramipexole. J Neurochem. 2013 Mar;124(6):844-54
All references(45)
Other
accession IDs
MGD-MRK-10206, MGI:2143677

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/16/2014
MGI 5.19
The Jackson Laboratory