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Gabra3
Gene Detail
 Symbol
Name
ID
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
MGI:95615
Synonyms Gabra-3
Feature Type protein coding gene
Genetic Map
Chromosome X
37.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(23)
Sequence Map
ChrX:72432681-72656848 bp, - strand
From VEGA annotation of GRCm38

  224168 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:20218  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 dog; 1 chicken

Gene Tree: Gabra3
Human
homologs
Human Homolog GABRA3, gamma-aminobutyric acid (GABA) A receptor, alpha 3
NCBI Gene ID 2556
neXtProt AC  NX_P34903
Human Chr (Location)  Xq28; chrX:151335634-151619831 (-)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(4) : Targeted(4)
 
Hemizygous males exhibit hyperactivity and an increased startle response with impaired prepulse inhibition.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (23 annotations)
Process chloride transport, gamma-aminobutyric acid signaling pathway, ...
Component cell junction, chloride channel complex, ...
Function chloride channel activity, extracellular ligand-gated ion channel activity, ...
External Resources: FuncBase
Expression Literature Summary: (6 records)
Data Summary: Results (98)    Tissues (52)    Images (21)
Theiler Stages: 22, 23, 24, 25, 28
Assay TypeResults
In situ reporter (knock in) 51
RT-PCR 47
cDNA source data(9)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(21) Genomic(9) cDNA(10) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000017849 (Evidence)
Ensembl Gene ModelENSMUSG00000031343 (Evidence)
Entrez Gene14396 (Evidence)
DFCITC1586082, TC1618518
DoTSDT.40183803, DT.91348041
NIA Mouse Gene IndexU039444, U065279
Consensus CDS ProjectCCDS30187.1
International Mouse Knockout Project StatusGabra3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017849 VEGA Gene Model | MGI Sequence Detail 224168 C57BL/6J ±  kb
transcript OTTMUST00000043201 VEGA | MGI Sequence Detail 1790 Not Applicable 
polypeptide OTTMUSP00000019433 VEGA | MGI Sequence Detail 533 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(4)
Polymorphisms RFLP(6) : SNPs(445 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR006028 Gamma-aminobutyric acid A receptor
InterPro IPR005433 Gamma-aminobutyric-acid A receptor, alpha 3 subunit
InterPro IPR001390 Gamma-aminobutyric-acid A receptor, alpha subunit
InterPro IPR006201 Neurotransmitter-gated ion-channel
InterPro IPR018000 Neurotransmitter-gated ion-channel, conserved site
InterPro IPR006202 Neurotransmitter-gated ion-channel ligand-binding
InterPro IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
Protein Ontology PR:000007768 gamma-aminobutyric acid receptor subunit alpha-3
References (Earliest) J:12515 Barnard PJ, et al., Localization of the GABA-A receptor alpha-3 subunit gene on the mouse X Chromosome. Cytogenet Cell Genet. 1989;51:958
(Latest) J:190498 Telegdy G, et al., Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice. Behav Brain Res. 2012 Jul 15;233(1):232-6
All references(70)
Other
accession IDs 		MGD-MRK-9924, MGD-MRK-9929
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory