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Gabrp Gene Detail
Summary
  • Symbol
    Gabrp
  • Name
    gamma-aminobutyric acid type A receptor subunit pi
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387597
    NCBI Gene: 216643
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:33500781-33528959 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 19.21 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    85 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387597
 protein coding gene Chr11:33500781-33528978 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018145
 protein coding gene Chr11:31861283-31890216 (-)
A/J MGP_AJ_G0018118
 protein coding gene Chr11:30644018-30673845 (-)
AKR/J MGP_AKRJ_G0018082
 protein coding gene Chr11:31606210-31634755 (-)
BALB/cJ MGP_BALBcJ_G0018087
 protein coding gene Chr11:30820358-30847713 (-)
C3H/HeJ MGP_C3HHeJ_G0017900
 protein coding gene Chr11:31542827-31574531 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018541
 protein coding gene Chr11:32891744-32924120 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016196
 protein coding gene Chr11:29144376-29170838 (-)
CAST/EiJ MGP_CASTEiJ_G0017464
 protein coding gene Chr11:31626227-31663272 (-)
CBA/J MGP_CBAJ_G0017873
 protein coding gene Chr11:34489054-34522873 (-)
DBA/2J MGP_DBA2J_G0017983
 protein coding gene Chr11:30411450-30440723 (-)
FVB/NJ MGP_FVBNJ_G0017977
 protein coding gene Chr11:30237495-30266028 (-)
LP/J MGP_LPJ_G0018055
 protein coding gene Chr11:32121199-32151599 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018001
 protein coding gene Chr11:35440955-35470679 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018580
 protein coding gene Chr11:31756596-31784691 (-)
PWK/PhJ MGP_PWKPhJ_G0017245
 protein coding gene Chr11:30600812-30629793 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017037
 protein coding gene Chr11:31468040-31496137 (-)
WSB/EiJ MGP_WSBEiJ_G0017513
 protein coding gene Chr11:31369344-31401730 (-)



Homology
more
  • Human Ortholog
    GABRP, gamma-aminobutyric acid type A receptor subunit pi
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GABRP, gamma-aminobutyric acid type A receptor subunit pi
  • Links
    NCBI Gene ID: 2568
    neXtProt AC: NX_O00591
    UniProt: O00591

  • Chr Location
    5q35.1; chr5:170763350-170814047 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Homozygous mutation of this gene does not appear to result in a phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    794
  • Tissues
    63
  • cDNA Data
    28
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020159 Ensembl Gene Model | MGI Sequence Detail 28179 C57BL/6J ±  kb
transcript ENSMUST00000020366 Ensembl | MGI Sequence Detail 3280 Not Applicable  
polypeptide ENSMUSP00000020366 Ensembl | MGI Sequence Detail 440 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000007780 gamma-aminobutyric acid receptor subunit pi
    (term hierarchy)
  • InterPro Domains
    IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alpha
    IPR008100 Gamma-aminobutyric-acid A receptor pi subunit
    IPR047032 Gamma-aminobutyric acid receptor subunit pi, transmembrane domain
    IPR038050 Neuronal acetylcholine receptor
    IPR006201 Neurotransmitter-gated ion-channel
    IPR018000 Neurotransmitter-gated ion-channel, conserved site
    IPR006202 Neurotransmitter-gated ion-channel ligand-binding domain
    IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamily
    IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
    IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamily
Molecular
Reagents
less
  • All nucleic 30
    cDNA 28
    Primer pair 1
    Other 1

    Microarray probesets 4
References
more
  • Summaries
    All 40
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory