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Tpr Gene Detail
Summary
  • Symbol
    Tpr
  • Name
    translocated promoter region, nuclear basket protein
  • Synonyms
    2610029M07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922066
    NCBI Gene: 108989
  • Alliance
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:150392838-150449935 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 63.84 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    656 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922066
protein coding gene Chr1:150392838-150449935 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016576
protein coding gene Chr1:155040706-155097762 (+)
A/J MGP_AJ_G0016558
protein coding gene Chr1:148793256-148851412 (+)
AKR/J MGP_AKRJ_G0016523
protein coding gene Chr1:153341248-153400002 (+)
BALB/cJ MGP_BALBcJ_G0016518
protein coding gene Chr1:149322347-149379387 (+)
C3H/HeJ MGP_C3HHeJ_G0016343
protein coding gene Chr1:153523798-153580945 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016979
protein coding gene Chr1:160415176-160475323 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014688
protein coding gene Chr1:141148729-141208272 (+)
CAST/EiJ MGP_CASTEiJ_G0015922
protein coding gene Chr1:152914626-152977519 (+)
CBA/J MGP_CBAJ_G0016317
protein coding gene Chr1:166085430-166142555 (+)
DBA/2J MGP_DBA2J_G0016423
protein coding gene Chr1:147847553-147905093 (+)
FVB/NJ MGP_FVBNJ_G0016421
protein coding gene Chr1:146301845-146359132 (+)
LP/J MGP_LPJ_G0016494
protein coding gene Chr1:156073425-156131607 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016447
protein coding gene Chr1:173776268-173837785 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017015
protein coding gene Chr1:153154514-153211904 (+)
PWK/PhJ MGP_PWKPhJ_G0015708
protein coding gene Chr1:146761378-146821360 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015495
protein coding gene Chr1:151932264-151998312 (+)
WSB/EiJ MGP_WSBEiJ_G0015985
protein coding gene Chr1:153228000-153286783 (+)



Homology
more
  • Human Ortholog
    TPR, translocated promoter region, nuclear basket protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TPR, translocated promoter region, nuclear basket protein
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 7175
    neXtProt AC: NX_P12270
    UniProt: P12270

  • Chr Location
    1q31.1; chr1:186311652-186375325 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 37753
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TPR
  • Gene Tree
    Tpr
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 108989 NCBI Gene Model | MGI Sequence Detail 57098 C57BL/6J ±  kb
transcript NM_133780 RefSeq | MGI Sequence Detail 7550 C57BL/6  
polypeptide F6ZDS4 UniProt | EBI | MGI Sequence Detail 2431 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 8
Other
Accession IDs
less
MGI:2138665
References
more
  • Summaries
    All 49
    Developmental Gene Expression 6
    Gene Ontology 9
    Phenotypes 15
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:245014 Giacomini C, et al., Lamin B1 protein is required for dendrite development in primary mouse cortical neurons. Mol Biol Cell. 2016 Jan 01;27(1):35-47

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory