About   Help   FAQ
Rnf135
Gene Detail
 Symbol
Name
ID
Rnf135
ring finger protein 135
MGI:1919206
Synonyms 0610037N03Rik, 2410006N06Rik, MGC13061, U 2-3-0
Feature Type protein coding gene
Genetic Map
Chromosome 11
47.59 cM, cytoband B5
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:80183851-80199757 bp, + strand
From VEGA annotation of GRCm38

  15907 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:12427  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Rnf135
Human
homologs
Human Homolog RNF135, ring finger protein 135
NCBI Gene ID 84282
neXtProt AC  NX_Q8IUD6
Human Synonyms  MMFD, REUL, Riplet
Human Chr (Location)  17q11.2; chr17:29297956-29326929 (+)  GRCh37.p10
Disease Associations  (1) Diseases Associated with Human RNF135
Alleles
and
phenotypes 		All alleles(52) : Gene trapped(52)
Gene Ontology
(GO)
classifications 		All GO classifications: (11 annotations)
Process innate immune response, positive regulation of interferon-beta production, ...
Component cytoplasm
Function ligase activity, metal ion binding, ...
External Resources: FuncBase
Expression Literature Summary: (3 records)
Data Summary: Results (77)    Tissues (56)    Images (5)
Theiler Stages: 10, 13, 16, 17, 20, 21, 22, 23, 28
Assay TypeResults
RNA in situ 69
RT-PCR 8
cDNA source data(10)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(11) cDNA(10) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000000220 (Evidence)
Ensembl Gene ModelENSMUSG00000020707 (Evidence)
Entrez Gene71956 (Evidence)
DFCITC1581413, TC1595619
DoTSDT.485307
NIA Mouse Gene IndexU013049
EC6.3.2.-
Consensus CDS ProjectCCDS25129.1
International Mouse Knockout Project StatusRnf135
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000220 VEGA Gene Model | MGI Sequence Detail 15907 C57BL/6J ±  kb
transcript OTTMUST00000000651 VEGA | MGI Sequence Detail 1984 Not Applicable 
polypeptide OTTMUSP00000000286 VEGA | MGI Sequence Detail 417 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(2)
Polymorphisms SNPs(20 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR001870 B30.2/SPRY domain
InterPro IPR003879 Butyrophylin-like
InterPro IPR008985 Concanavalin A-like lectin/glucanases superfamily
InterPro IPR003877 SPla/RYanodine receptor SPRY
InterPro IPR006574 SPRY-associated
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
InterPro IPR017907 Zinc finger, RING-type, conserved site
Protein Ontology PR:000014083 E3 ubiquitin-protein ligase RNF135
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(34)
Other
accession IDs 		MGI:1915638
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory