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Cryl1
Gene Detail
 Symbol
Name
ID
Cryl1
crystallin, lambda 1
MGI:1915881
Synonyms 1110025H08Rik, A230106J09Rik
Feature Type protein coding gene
Genetic Map
Chromosome 14
30.10 cM, cytoband C2
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr14:57275034-57398483 bp, - strand
From NCBI annotation of GRCm38

  123450 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:9322  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: 3-hydroxyacyl-CoA dehydrogenase
Gene Tree: Cryl1
Human
homologs
Human Homolog CRYL1, crystallin, lambda 1
NCBI Gene ID 51084
neXtProt AC  NX_Q9Y2S2
Human Synonyms  GDH, lambda-CRY
Human Chr (Location)  13q12.11; chr13:20977806-21100012 (-)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(5) : Targeted(2) Gene trapped(3)
Gene Ontology
(GO)
classifications 		All GO classifications: (11 annotations)
Process fatty acid metabolic process, oxidation-reduction process
Component cytoplasm
Function 3-hydroxyacyl-CoA dehydrogenase activity, coenzyme binding, ...
External Resources: FuncBase
Expression Literature Summary: (5 records)
Data Summary: Results (243)    Tissues (196)    Images (20)
Theiler Stages: 1, 2, 3, 5, 22, 23, 25, 28
Assay TypeResults
RNA in situ 229
RT-PCR 14
cDNA source data(62)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(64) cDNA(62) Primer pair(2)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000021947 (Evidence)
Entrez Gene68631 (Evidence)
UniGene25539
DFCITC1576459, TC1588308
DoTSDT.528346, DT.55239325, DT.94281175
NIA Mouse Gene IndexU035623
EC1.1.1.45
Consensus CDS ProjectCCDS27155.1
International Mouse Knockout Project StatusCryl1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 68631 NCBI Gene Model | MGI Sequence Detail 123450 C57BL/6J ±  kb
transcript NM_030004 RefSeq | MGI Sequence Detail 1410 C57BL/6 
polypeptide Q99KP3 UniProt | EBI | MGI Sequence Detail 319 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(3)
Polymorphisms SNPs(201 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR022694 3-hydroxyacyl-CoA dehydrogenase
InterPro IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site
InterPro IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal
InterPro IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding
InterPro IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
InterPro IPR013328 Dehydrogenase, multihelical
InterPro IPR016040 NAD(P)-binding domain
Protein Ontology PR:000005920 lambda-crystallin
Graphical View of Protein Domain Structure
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(41)
Other
accession IDs 		MGI:1925166, MGI:2145872
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/22/2013
MGI 5.13 		The Jackson Laboratory