About   Help   FAQ
Wls
Gene Detail
 Symbol
Name
ID
Wls
wntless homolog (Drosophila)
MGI:1915401
Synonyms 5031439A09Rik, Gpr177
Feature Type protein coding gene
Genetic Map
Chromosome 3
82.65 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:159839695-159935175 bp, + strand
From NCBI annotation of GRCm38

  95481 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:11779  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Wls
Human
homologs
Human Homolog WLS, wntless homolog (Drosophila)
NCBI Gene ID 79971
neXtProt AC  NX_Q5T9L3
Human Synonyms  C1orf139, EVI, GPR177, mig-14, MRP
Human Chr (Location)  1p31.3; chr1:68564142-68698284 (-)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(9) : Targeted(6) Gene trapped(3)
 
Mice homozygous for null alleles exhibit impaired body axis and triploblastic development dying prior to E10.5.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (11 annotations)
Process anterior/posterior axis specification, mesoderm formation, ...
Component cytoplasmic vesicle, Golgi apparatus, ...
Function protein binding, Wnt-protein binding
External Resources: FuncBase
Expression Literature Summary: (8 records)
Data Summary: Results (162)    Tissues (79)    Images (53)
Theiler Stages: 21, 22, 23
Assay TypeResults
Immunohistochemistry 78
RNA in situ 84
cDNA source data(241)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(241) cDNA(241)
Microarray probesets(9)
Other database
links
Ensembl Gene ModelENSMUSG00000028173 (Evidence)
Entrez Gene68151 (Evidence)
UniGene6766
DFCITC1573412, TC1584678, TC1584749, TC1590725, TC1592619, TC1643444, TC1742809
DoTSDT.101392672, DT.101738887, DT.103571331, DT.532040, DT.60101023, DT.91333856, DT.91567960, DT.94365974
NIA Mouse Gene IndexU004030
Consensus CDS ProjectCCDS38684.1
International Mouse Knockout Project StatusWls
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 68151 NCBI Gene Model | MGI Sequence Detail 95481 C57BL/6J ±  kb
transcript NR_037590 RefSeq | MGI Sequence Detail 2777 C57BL/6 
polypeptide Q6DID7 UniProt | EBI | MGI Sequence Detail 541 Not Applicable 

For the selected sequences
All sequences(58) RefSeq(3) UniProt(2)
Polymorphisms SNPs(217 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR009551 Protein wntless
Protein Ontology PR:000030622 protein wntless homolog
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:193842 Lu C, et al., Wnt-mediated reciprocal regulation between cartilage and bone development during endochondral ossification. Bone. 2013 Apr;53(2):566-74
All references(43)
Other
accession IDs 		MGI:2139641, MGI:2139844
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory