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Rgs10
Gene Detail
 Symbol
Name
ID
Rgs10
regulator of G-protein signalling 10
MGI:1915115
Synonyms 2310010N19Rik
Feature Type protein coding gene
Genetic Map
Chromosome 7
70.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:128373621-128418758 bp, - strand
From VEGA annotation of GRCm38

  45138 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:37710  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: regulator of G protein signaling, RGS4 type
Gene Tree: Rgs10
Human
homologs
Human Homolog RGS10, regulator of G-protein signaling 10
NCBI Gene ID 6001
neXtProt AC  NX_O43665
Human Chr (Location)  10q25; chr10:121259339-121302222 (-)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(9) : Targeted(1) Gene trapped(8)
 
A gene trap mutation of this gene results in impaired glucose tolerance and increased fasting glucose levels whereas a targeted knockout shows defects in osteoclast differentiation and in the skeleton.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (11 annotations)
Process negative regulation of signal transduction, termination of G-protein coupled receptor signaling pathway
Component axon terminus, cytoplasm, ...
Function GTPase activator activity, protein binding
External Resources: FuncBase
Expression Literature Summary: (4 records)
Data Summary: Results (14)    Tissues (7)   
Theiler Stages: 1, 2, 3, 5, 28
Assay TypeResults
RT-PCR 14
cDNA source data(39)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(40) cDNA(39) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000022902 (Evidence)
Ensembl Gene ModelENSMUSG00000030844 (Evidence)
Entrez Gene67865 (Evidence)
UniGene18635
DFCITC1578141
DoTSDT.531098, DT.94256530
NIA Mouse Gene IndexU029321
Consensus CDS ProjectCCDS21896.1
International Mouse Knockout Project StatusRgs10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022902 VEGA Gene Model | MGI Sequence Detail 45138 C57BL/6J ±  kb
transcript OTTMUST00000055088 VEGA | MGI Sequence Detail 880 Not Applicable 
polypeptide OTTMUSP00000026329 VEGA | MGI Sequence Detail 181 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(2) UniProt(3)
Polymorphisms RFLP(1) : SNPs(178 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR024066 Regulator of G-protein signaling, domain 1
InterPro IPR000342 Regulator of G protein signalling
InterPro IPR016137 Regulator of G protein signalling superfamily
Protein Ontology PR:000013945 regulator of G-protein signaling 10
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(42)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/05/2013
MGI 5.13 		The Jackson Laboratory