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Gabrq
Gene Detail
 Symbol
Name
ID
Gabrq
gamma-aminobutyric acid (GABA) A receptor, subunit theta
MGI:1888498
Feature Type protein coding gene
Genetic Map
Chromosome X
37.29 cM, cytoband A6
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:72825178-72842602 bp, + strand
From VEGA annotation of GRCm38

  17425 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10233  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Gabrq

Human
homologs
Human Homolog GABRQ, gamma-aminobutyric acid (GABA) A receptor, theta
NCBI Gene ID 55879
neXtProt AC  NX_Q9UN88
Human Synonyms  THETA
Human Chr (Location)  Xq28; chrX:152638183-152653362 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from APF )
 
Males hemizygous for a mutation in this gene exhibit decreased prepulse inhibition.
 
Interactions
Gabrq interacts with 389 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process chloride transport, gamma-aminobutyric acid signaling pathway, ...
Component cell junction, chloride channel complex, ...
Function chloride channel activity, extracellular ligand-gated ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (86)    Tissues (52)    Images (15)
Theiler Stages: 28
Assay TypeResults
In situ reporter (knock in) 48
RT-PCR 38
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(6) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000017852 (Evidence)
Ensembl Gene ModelENSMUSG00000031344 (Evidence)
Entrez Gene57249 (Evidence)
DFCITC1593486, TC1617403
DoTSDT.101715019, DT.99852916
NIA Mouse Gene IndexU019927
Consensus CDS ProjectCCDS30188.1, CCDS72390.1
International Mouse Knockout Project StatusGabrq
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017852 VEGA Gene Model | MGI Sequence Detail 17425 C57BL/6J ±  kb
transcript OTTMUST00000043205 VEGA | MGI Sequence Detail 2000 Not Applicable 
polypeptide OTTMUSP00000019435 VEGA | MGI Sequence Detail 638 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(6) UniProt(4)
Polymorphisms SNPs within 2kb(67 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006028 Gamma-aminobutyric acid A receptor
InterPro IPR008101 Gamma-aminobutyric-acid A receptor theta subunit
InterPro IPR006201 Neurotransmitter-gated ion-channel
InterPro IPR018000 Neurotransmitter-gated ion-channel, conserved site
InterPro IPR006202 Neurotransmitter-gated ion-channel ligand-binding
InterPro IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
Protein Ontology PR:000007781 gamma-aminobutyric acid receptor subunit theta
References (Earliest) J:62100 Sinkkonen ST, et al., GABA(A) receptor epsilon and theta subunits display unusual structural variation between species and are enriched in the rat locus ceruleus. J Neurosci. 2000 May 15;20(10):3588-95
(Latest) J:194542 Ghai R, et al., Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E643-52
All references(25)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory