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Trpm5
Gene Detail
 Symbol
Name
ID
Trpm5
transient receptor potential cation channel, subfamily M, member 5
MGI:1861718
Synonyms 9430099A16Rik, Ltrpc5, Mtr1
Feature Type protein coding gene
Genetic Map
Chromosome 7
88.11 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr7:143069153-143094642 bp, - strand
From VEGA annotation of GRCm38

  25490 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22818  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: transient receptor potential cation channels TRPM4/TRPM5
Gene Tree: Trpm5

Human
homologs
Human Homolog TRPM5, transient receptor potential cation channel, subfamily M, member 5
NCBI Gene ID 29850
neXtProt AC  NX_Q9NZQ8
Human Synonyms  LTRPC5, MTR1
Human Chr (Location)  11p15.5; chr11:2404515-2423402 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice demonstrate abnormal taste perception, responding to sour and salty stimuli but not to sweet, or bitter stimuli.
 
Interactions
Trpm5 interacts with 115 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process ion transmembrane transport, ion transport, ...
Component integral component of membrane, membrane, ...
Function calcium activated cation channel activity, potassium channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (216)    Tissues (124)    Images (9)
Theiler Stages: 20, 22, 23, 24, 25, 26, 28
Assay TypeResults
RNA in situ 73
In situ reporter (knock in) 35
RT-PCR 108
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(25) Genomic(2) cDNA(16) Primer pair(7)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000022683 (Evidence)
Ensembl Gene ModelENSMUSG00000009246 (Evidence)
Entrez Gene56843 (Evidence)
UniGene286668
DFCITC1585762, TC1616422, TC1683575
DoTSDT.101352813, DT.101722863, DT.87048507, DT.91387732, DT.91394818, DT.94236103
NIA Mouse Gene IndexU029493
Consensus CDS ProjectCCDS52462.1
International Mouse Knockout Project StatusTrpm5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022683 VEGA Gene Model | MGI Sequence Detail 25490 C57BL/6J ±  kb
transcript OTTMUST00000054375 VEGA | MGI Sequence Detail 4123 Not Applicable 
polypeptide OTTMUSP00000025953 VEGA | MGI Sequence Detail 1158 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(6) UniProt(4)
Polymorphisms PCR(1) : SNPs within 2kb(141 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000016701 transient receptor potential cation channel subfamily M member 5
References (Earliest) J:63552 Yatsuki H, et al., Sequence-based structural features between Kvlqt1 and Tapa1 on mouse chromosome 7F4/F5 corresponding to the Beckwith-Wiedemann syndrome region on human 11p15.5: long-stretches of unusually well conserved intronic sequences of kvlqt1 between mouse and human. DNA Res. 2000 Jun 30;7(3):195-206
(Latest) J:211361 Deckmann K, et al., Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes. Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8287-92
All references(74)
Other
accession IDs
MGI:2443185

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory