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Peg12 Gene Detail
Summary
  • Symbol
    Peg12
  • Name
    paternally expressed 12
  • Synonyms
    Frat3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351637
    NCBI Gene: 27412
  • Gene Overview
    MyGene.info: FRAT2
Location & Maps
more
  • Sequence Map
    Chr7:62461871-62464510 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2640 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    FRAT2, frequently rearranged in advanced T-cell lymphomas 2
  • Human Ortholog
    FRAT2, frequently rearranged in advanced T-cell lymphomas 2
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 23401
    neXtProt AC: NX_O75474

  • Chr Location
    10q24.1; chr10:97332497-97334701 (-)  GRCh38.p2

  • HCOP
    human homology predictions: FRAT2
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with Peg12 mouse models

Human Disease Mouse Models
       Prader-Willi Syndrome; PWS   OMIM: 176270
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    11 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Peg12
  • Incidental Mutations
Homozygous mice are healthy and fertile with no obvious abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000059567 VEGA Gene Model | MGI Sequence Detail 2640 C57BL/6J ±  kb
transcript OTTMUST00000146087 VEGA | MGI Sequence Detail 2640 Not Applicable  
polypeptide OTTMUSP00000076116 VEGA | MGI Sequence Detail 283 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    23 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR008014 Glycogen synthase kinase-3 binding protein
Molecular
Reagents
less
  • All nucleic 11
    Genomic 1
    cDNA 5
    Primer pair 5

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Developmental Gene Expression 10
    Diseases 1
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:58550 Jonkers J, et al., In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3. Mech Dev. 1999 Nov;88(2):183-94
  • Latest
    J:217174 Nakagaki A, et al., Imprinting analysis of the mouse chromosome 7C region in DNMT1-null embryos. Gene. 2014 Dec 10;553(1):63-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory