About   Help   FAQ
Slc35a1
Gene Detail
 Symbol
Name
ID
Slc35a1
solute carrier family 35 (CMP-sialic acid transporter), member 1
MGI:1345622
Feature Type protein coding gene
Genetic Map
Chromosome 4
16.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:34663257-34687438 bp, - strand
From VEGA annotation of GRCm38

  24182 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:38181  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: nucleotide-sugar transporter
Gene Tree: Slc35a1
Human
homologs
Human Homolog SLC35A1, solute carrier family 35 (CMP-sialic acid transporter), member A1
NCBI Gene ID 10559
neXtProt AC  NX_P78382
Human Synonyms  CDG2F, CMPST, CST, hCST
Human Chr (Location)  6q15; chr6:88182643-88222057 (+)  GRCh37.p10
Disease Associations  (1) Diseases Associated with Human SLC35A1
Alleles
and
phenotypes 		All alleles(4) : Gene trapped(4)
 
Homozygous mutation of this gene results in lethality before weaning.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (11 annotations)
Process carbohydrate transport, nucleotide-sugar transport, ...
Component Golgi apparatus, Golgi membrane, ...
Function nucleotide-sugar transmembrane transporter activity, sugar:hydrogen symporter activity
External Resources: FuncBase
Expression Literature Summary: (3 records)
Data Summary: Results (13)    Tissues (12)    Images (1)
Theiler Stages: 10, 18, 23, 25, 28
Assay TypeResults
RNA in situ 1
Northern blot 12
cDNA source data(63)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(65) cDNA(63) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000006413 (Evidence)
Ensembl Gene ModelENSMUSG00000028293 (Evidence)
Entrez Gene24060 (Evidence)
UniGene281885
DFCITC1577342, TC1731358
DoTSDT.532699
NIA Mouse Gene IndexU024932
Consensus CDS ProjectCCDS18030.1
International Mouse Knockout Project StatusSlc35a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006413 VEGA Gene Model | MGI Sequence Detail 24182 C57BL/6J ±  kb
transcript OTTMUST00000014620 VEGA | MGI Sequence Detail 2039 Not Applicable 
polypeptide OTTMUSP00000006797 VEGA | MGI Sequence Detail 336 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(2)
Polymorphisms SNPs(161 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR007271 Nucleotide-sugar transporter
InterPro IPR021189 UDP/CMP-sugar transporter
InterPro IPR004689 UDP-galactose transporter
Protein Ontology PR:000015089 CMP-sialic acid transporter
References (Earliest) J:57553 Eckhardt M, et al., Expression cloning of the Golgi CMP-sialic acid transporter. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7572-6
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(33)
Other
accession IDs 		MGI:2140125, MGI:2140225
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory