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Chd3
Gene Detail
 Symbol
Name
ID
Chd3
chromodomain helicase DNA binding protein 3
MGI:1344395
Synonyms 2600010P09Rik, Chd7, Mi-2 alpha, Prp7, Prp9-1
Feature Type protein coding gene
Genetic Map
Chromosome 11
42.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:69343273-69369406 bp, - strand
From VEGA annotation of GRCm38

  26134 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:62693  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Chd3
Human
homologs
Human Homolog CHD3, chromodomain helicase DNA binding protein 3
NCBI Gene ID 1107
neXtProt AC  NX_Q12873
Human Synonyms  Mi-2a, Mi2-ALPHA, ZFH
Human Chr (Location)  17P13.1; chr17:7788123-7816075 (+)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(8) : Targeted(1) Gene trapped(7)
Gene Ontology
(GO)
classifications 		All GO classifications: (13 annotations)
Process centrosome organization, chromatin assembly or disassembly, ...
Component centrosome, cytoplasm, ...
Function helicase activity, metal ion binding, ...
External Resources: FuncBase
Expression Literature Summary: (7 records)
Data Summary: Results (49)    Tissues (38)    Images (4)
Theiler Stages: 2, 3, 4, 5, 22, 23, 28
Assay TypeResults
RNA in situ 26
Northern blot 8
RT-PCR 15
cDNA source data(258)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(259) cDNA(258) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000005975 (Evidence)
Ensembl Gene ModelENSMUSG00000018474 (Evidence)
Entrez Gene216848 (Evidence)
UniGene178246
DFCITC1574151, TC1588069, TC1603194, TC1638884, TC1649172
DoTSDT.101390789, DT.481400, DT.536523, DT.91308758, DT.94263189, DT.94363995
NIA Mouse Gene IndexU032957
Consensus CDS ProjectCCDS48825.2
International Mouse Knockout Project StatusChd3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005975 VEGA Gene Model | MGI Sequence Detail 26134 C57BL/6J ±  kb
transcript OTTMUST00000013358 VEGA | MGI Sequence Detail 7261 Not Applicable 
polypeptide OTTMUSP00000006184 VEGA | MGI Sequence Detail 2055 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(2) UniProt(10)
Polymorphisms SNPs(73 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR012957 CHD, C-terminal 2
InterPro IPR012958 CHD, N-terminal
InterPro IPR023780 Chromo domain
InterPro IPR023779 Chromo domain, conserved site
InterPro IPR016197 Chromo domain-like
InterPro IPR000953 Chromo domain/shadow
InterPro IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
InterPro IPR009462 Domain of unknown function DUF1086
InterPro IPR009463 Domain of unknown function DUF1087
InterPro IPR001650 Helicase, C-terminal
InterPro IPR014001 Helicase, superfamily 1/2, ATP-binding domain
InterPro IPR009071 High mobility group, superfamily
InterPro IPR000330 SNF2-related
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000005409 chromodomain-helicase-DNA-binding protein 3
References (Earliest) J:44866 Ermekova KS, et al., The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled. J Biol Chem. 1997 Dec 26;272(52):32869-77
(Latest) J:177729 Fessing MY, et al., p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39
All references(41)
Other
accession IDs 		MGI:1919700, MGI:1934942
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory