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Hivep2
Gene Detail
 Symbol
Name
ID
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
MGI:1338076
Synonyms MIBP1, Schnurri-2, Shn-2
Feature Type protein coding gene
Genetic Map
Chromosome 10
5.14 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:13966379-14151376 bp, + strand
From Ensembl annotation of GRCm38

  184998 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:4900  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Hivep2
Human
homologs
Human Homolog HIVEP2, human immunodeficiency virus type I enhancer binding protein 2
NCBI Gene ID 3097
neXtProt AC  NX_P31629
Human Synonyms  HIV-EP2, MBP-2, MIBP1, SHN2, ZAS2, ZNF40B
Human Chr (Location)  6q23-q24; chr6:143072604-143266338 (-)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(3) : Targeted(3)
 
Mice homozygous for a knock-out allele display abnormal thymus anatomy, severely defective positive selection of CD4+ and CD8+ cells, and enhanced T-helper 2 cell differentiation.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (9 annotations)
Process regulation of transcription, DNA-dependent, signal transduction, ...
Component nucleus, transcription factor complex
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression Literature Summary: (6 records)
Data Summary: Results (122)    Tissues (77)    Images (26)
Theiler Stages: 15, 17, 19, 21, 23, 28
Assay TypeResults
RNA in situ 122
cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(18) cDNA(18)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000015501 (Evidence)
Entrez Gene15273 (Evidence)
DFCITC1582525, TC1605550, TC1606049
DoTSDT.110615241, DT.110615263, DT.486962, DT.91312292, DT.91379897, DT.91561657, DT.94217243
Consensus CDS ProjectCCDS23704.1
International Mouse Knockout Project StatusHivep2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015501 Ensembl Gene Model | MGI Sequence Detail 184998 C57BL/6J ±  kb
transcript ENSMUST00000015645 Ensembl | MGI Sequence Detail 9766 Not Applicable 
polypeptide ENSMUSP00000015645 Ensembl | MGI Sequence Detail 2430 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(2)
Polymorphisms SNPs(1357 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000008605 transcription factor HIVEP2
References (Earliest) J:54634 Dorflinger U, et al., Activation of somatostatin receptor II expression by transcription factors MIBP1 and SEF-2 in the murine brain. Mol Cell Biol. 1999 May;19(5):3736-47
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/22/2013
MGI 5.13 		The Jackson Laboratory