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Naip1
Gene Detail
 Symbol
Name
ID
Naip1
NLR family, apoptosis inhibitory protein 1
MGI:1298223
Synonyms Birc1a, D13Lsd1, Naip
Feature Type protein coding gene
Genetic Map
Chromosome 13
53.18 cM, cytoband D1-D3
Detailed Genetic Map ± 1 cM


Mapping data(13)
Sequence Map
Chr13:100407770-100446406 bp, - strand
From Ensembl annotation of GRCm38

  38637 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:113589  Vertebrate Homology Class
1 human; 3 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle

Protein SuperFamily: neuronal apoptosis inhibitory protein
Gene Tree: Naip1
Human
homologs
Human Homolog NAIP, NLR family, apoptosis inhibitory protein
NCBI Gene ID 4671
neXtProt AC  NX_Q13075
Human Synonyms  BIRC1, NLRB1, psiNAIP
Human Chr (Location)  5q13.2; chr5:70264310-70320941 (-)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(6) : Targeted(6)
 
Mice homozygous for disruptions in this gene display a normal phenotype.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (20 annotations)
Process apoptotic process, cellular response to estrogen stimulus, ...
Component basolateral plasma membrane, cytoplasm, ...
Function ATP binding, cysteine-type endopeptidase inhibitor activity, ...
External Resources: FuncBase
Expression Literature Summary: (5 records)
Data Summary: Results (122)    Tissues (67)    Images (3)
Theiler Stages: 22, 23, 28
Assay TypeResults
RNA in situ 24
In situ reporter (knock in) 48
RT-PCR 50
cDNA source data(9)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(36) Genomic(20) cDNA(9) Primer pair(6) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000021640 (Evidence)
Entrez Gene17940 (Evidence)
UniGene6898
DoTSDT.485607, DT.91335568
NIA Mouse Gene IndexU035107
Consensus CDS ProjectCCDS26729.1
International Mouse Knockout Project StatusNaip1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021640 Ensembl Gene Model | MGI Sequence Detail 38637 C57BL/6J ±  kb
transcript ENSMUST00000022142 Ensembl | MGI Sequence Detail 5353 Not Applicable 
polypeptide ENSMUSP00000022142 Ensembl | MGI Sequence Detail 1403 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(2)
Polymorphisms PCR(3) : SNPs(281 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR001370 Baculoviral inhibition of apoptosis protein repeat
InterPro IPR007111 NACHT nucleoside triphosphatase
Protein Ontology PR:000011552 baculoviral IAP repeat-containing protein 1a
References (Earliest) J:37707 Scharf JM, et al., The mouse region syntenic for human spinal muscular atrophy lies within the Lgn1 critical interval and contains multiple copies of Naip exon 5. Genomics. 1996 Dec 15;38(3):405-17
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(49)
Other
accession IDs 		MGD-MRK-38374, MGD-MRK-39477, MGI:109329, MGI:109478, MGI:2145401
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory