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Psmd4
Gene Detail
 Symbol
Name
ID
Psmd4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
MGI:1201670
Synonyms Af1, angiocidin, Mcb1, multiubiquitin-chain-binding protein
Feature Type protein coding gene
Genetic Map
Chromosome 3
40.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr3:95032694-95042614 bp, - strand
From VEGA annotation of GRCm38

  9921 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:55691  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 chicken; 1 zebrafish

Protein SuperFamily: 26S proteasome regulatory complex, non-ATPase subcomplex, RPN10/PSMD4 subunit
Gene Tree: Psmd4
Human
homologs
Human Homolog PSMD4, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
NCBI Gene ID 5710
neXtProt AC  NX_P55036
Human Synonyms  AF, AF-1, ASF, MCB1, pUB-R5, Rpn10, S5A
Human Chr (Location)  1q21.3; chr1:151227197-151239955 (+)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(29) : Targeted(5) Gene trapped(24)
 
Mice homozygous for a null allele exhibit embryonic lethality and abnormal embryogenesis.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (6 annotations)
Process ubiquitin-dependent protein catabolic process
Component cytoplasm, proteasome accessory complex, ...
Function molecular_function
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Results (21)    Tissues (21)    Images (1)
Theiler Stages: 15, 23, 28
Assay TypeResults
RNA in situ 19
RT-PCR 2
cDNA source data(9)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(11) cDNA(9) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000019658 (Evidence)
Ensembl Gene ModelENSMUSG00000005625 (Evidence)
Entrez Gene19185 (Evidence)
DFCITC1585537, TC1591505, TC1592834, TC1600736, TC1601803, TC1608000, TC1621801, TC1629587
DoTSDT.101133405, DT.101133408, DT.101336650, DT.536211, DT.94313038
Consensus CDS ProjectCCDS38541.1
International Mouse Knockout Project StatusPsmd4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019658 VEGA Gene Model | MGI Sequence Detail 9921 C57BL/6J ±  kb
transcript OTTMUST00000047018 VEGA | MGI Sequence Detail 1276 Not Applicable 
polypeptide OTTMUSP00000021245 VEGA | MGI Sequence Detail 379 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(2) UniProt(4)
Polymorphisms SNPs(33 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR027040 Proteasome subunit Rpn10
InterPro IPR003903 Ubiquitin interacting motif
InterPro IPR002035 von Willebrand factor, type A
Protein Ontology PR:000002181 26S proteasome non-ATPase regulatory subunit 4
References (Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(38)
Other
accession IDs 		MGD-MRK-36380, MGI:107803
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/05/2013
MGI 5.13 		The Jackson Laboratory