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Rbbp4
Gene Detail
 Symbol
Name
ID
Rbbp4
retinoblastoma binding protein 4
MGI:1194912
Synonyms CAF-1 p48 subunit
Feature Type protein coding gene
Genetic Map
Chromosome 4
63.26 cM, cytoband D2.3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:129307100-129335370 bp, - strand
From VEGA annotation of GRCm38

  28271 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:21153  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: MSI1 protein
Gene Tree: Rbbp4
Human
homologs
Human Homolog RBBP4, retinoblastoma binding protein 4
NCBI Gene ID 5928
neXtProt AC  NX_Q09028
Human Synonyms  NURF55, RBAP48
Human Chr (Location)  1p35.1; chr1:33116749-33151812 (+)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(44) : Targeted(2) Gene trapped(42)
Gene Ontology
(GO)
classifications 		All GO classifications: (18 annotations)
Process cell cycle, chromatin assembly, ...
Component CAF-1 complex, ESC/E(Z) complex, ...
Function DNA-dependent ATPase activity, histone deacetylase binding
External Resources: FuncBase
Expression Literature Summary: (9 records)
Data Summary: Results (29)    Tissues (23)    Images (2)
Theiler Stages: 15, 19, 24, 28
Assay TypeResults
RNA in situ 16
Western blot 2
RNase protection 11
cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(15) cDNA(13) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000009619 (Evidence)
Ensembl Gene ModelENSMUSG00000057236 (Evidence)
Entrez Gene19646 (Evidence)
DFCITC1571869, TC1601862, TC1614101, TC1636158
NIA Mouse Gene IndexU025550
Consensus CDS ProjectCCDS18688.1
International Mouse Knockout Project StatusRbbp4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009619 VEGA Gene Model | MGI Sequence Detail 28271 C57BL/6J ±  kb
transcript OTTMUST00000022134 VEGA | MGI Sequence Detail 4407 Not Applicable 
polypeptide OTTMUSP00000010088 VEGA | MGI Sequence Detail 425 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(2)
Polymorphisms SNPs(143 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR020472 G-protein beta WD-40 repeat
InterPro IPR022052 Histone-binding protein RBBP4
InterPro IPR001680 WD40 repeat
InterPro IPR019775 WD40 repeat, conserved site
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000013776 histone-binding protein RBBP4
References (Earliest) J:113043 Lee EY, et al., Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 1994 Sep 1;8(17):2008-21
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(43)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory