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Ldb2
Gene Detail
 Symbol
Name
ID
Ldb2
LIM domain binding 2
MGI:894670
Synonyms CLIM1, CLIM-1a, CLIM-1b, CLP-36, Ldb3
Feature Type protein coding gene
Genetic Map
Chromosome 5
24.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:44472133-44799707 bp, - strand
From NCBI annotation of GRCm38

  327575 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:989  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: LIM-domain-binding protein
Gene Tree: Ldb2
Human
homologs
Human Homolog LDB2, LIM domain binding 2
NCBI Gene ID 9079
neXtProt AC  NX_O43679
Human Synonyms  CLIM1, LDB1
Human Chr (Location)  4p16; chr4:16503164-16900424 (-)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(1) : Targeted(1)
 
Homozygous mutation of this gene results in no obvious phenotype.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (13 annotations)
Process epithelial structure maintenance, hair follicle development, ...
Component nucleus, transcription factor complex
Function enzyme binding, LIM domain binding, ...
External Resources: FuncBase
Expression Literature Summary: (26 records)
Data Summary: Results (90)    Tissues (83)    Images (8)
Theiler Stages: 2, 3, 4, 5, 15, 17, 18, 19, 20, 21, 23, 26, 28
Assay TypeResults
RNA in situ 75
RT-PCR 15
cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(15) cDNA(13) Primer pair(1) Other(1)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000039706 (Evidence)
Entrez Gene16826 (Evidence)
DFCITC1582170, TC1612074, TC1774420
DoTSDT.101381925, DT.40181101, DT.99822105, DT.99855203
NIA Mouse Gene IndexU026165
Consensus CDS ProjectCCDS19271.1
International Mouse Knockout Project StatusLdb2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 16826 NCBI Gene Model | MGI Sequence Detail 327575 C57BL/6J ±  kb
transcript NM_001077398 RefSeq | MGI Sequence Detail 2622 C57BL/6 
polypeptide O55203 UniProt | EBI | MGI Sequence Detail 373 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(4) UniProt(1)
Polymorphisms SNPs(1567 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR002691 LIM-domain binding protein
Protein Ontology PR:000009737 LIM domain-binding protein 2
Graphical View of Protein Domain Structure
References (Earliest) J:41552 Agulnick AD, et al., Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins. Nature. 1996 21;384(6606):270-2
(Latest) J:192580 Diaz-Alonso J, et al., The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis. J Neurosci. 2012 Nov 21;32(47):16651-65
All references(53)
Other
accession IDs 		MGI:2140800, MGI:2141166, MGI:894768
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/22/2013
MGI 5.13 		The Jackson Laboratory