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sky Gene Detail
Summary
  • Symbol
    sky
  • Name
    severe kyphosis
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:3612271
Location & Maps
more
  • Genetic Map
    Chromosome 14, Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for this spontaneous mutation exhibit severe kyphosis, intervertebral disk degeneration, premature death, eyes open at birth, and small granulomas in brown fat. Mice also do not breed.
References
more
  • Summaries
    All 1
    Phenotypes 1
  • Earliest
    J:136875 Karst SY, et al., Severe kyphosis (sky); a new skeletal mutation on Chromosome 14. MGI Direct Data Submission. 2008;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory