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sky Gene Detail
Summary
  • Symbol
    sky
  • Name
    severe kyphosis
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:3612271
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr14:3050001-9987934 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for this spontaneous mutation exhibit severe kyphosis, intervertebral disk degeneration, premature death, eyes open at birth, and small granulomas in brown fat. Mice also do not breed.
References
more
  • Summaries
    All 1
    Phenotypes 1
  • Earliest
    J:136875 Karst SY, et al., Severe kyphosis (sky); a new skeletal mutation on Chromosome 14. MGI Direct Data Submission. 2008;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory