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Pcdha Complex/Cluster/Region Detail
Summary
  • Symbol
    Pcdha
  • Name
    protocadherin alpha cluster
  • Synonyms
    PCDHA@
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:3719085
  • Cluster Members
    Pcdha1, Pcdha2, Pcdha3 ... (14 members)
Location &
Maps
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  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 18, Syntenic
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    24 phenotypes from 11 alleles in 6 genetic backgrounds
    2 phenotypes from multigenic genotypes
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for an allele that produces only isoform A exhibit enhanced contextual conditioning, spatial working memory and serotonin levels.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
    Molecular
    Reagents
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    • All nucleic 6
      cDNA 3
      Primer pair 3
    References
    more
    • Summaries
      All 23
      Developmental Gene Expression 9
      Phenotypes 15
    • Earliest
      J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
    • Latest
      J:277192 Shao Z, et al., Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia. Nat Neurosci. 2019 Feb;22(2):229-242

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    12/03/2019
    MGI 6.14
    The Jackson Laboratory