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Arnt2
Gene Detail
 Symbol
Name
ID
Arnt2
aryl hydrocarbon receptor nuclear translocator 2
MGI:107188
Synonyms bHLHe1, mKIAA0307
Feature Type protein coding gene
Genetic Map
Chromosome 7
48.35 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr7:84246278-84361673 bp, - strand
From NCBI annotation of GRCm38

  115396 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:7230  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: aryl hydrocarbon receptor nuclear translocator
Gene Tree: Arnt2
Human
homologs
Human Homolog ARNT2, aryl-hydrocarbon receptor nuclear translocator 2
NCBI Gene ID 9915
neXtProt AC  NX_Q9HBZ2
Human Synonyms  bHLHe1
Human Chr (Location)  15q24; chr15:80696692-80890278 (+)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(4) : Targeted(3) Gene trapped(1)
 
Mice homozygous for targeted mutations that inactivate this gene die shortly after birth, displaying impaired development of secretory neurons in the hypothalamus.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (26 annotations)
Process central nervous system development, negative regulation of apoptotic process, ...
Component cytoplasm, nucleus, ...
Function aryl hydrocarbon receptor binding, DNA binding, ...
External Resources: FuncBase
Expression Literature Summary: (15 records)
Data Summary: Results (453)    Tissues (280)    Images (26)
Theiler Stages: 2, 3, 4, 5, 15, 17, 19, 21, 23, 25, 28
Assay TypeResults
RNA in situ 438
RT-PCR 15
cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(24) Genomic(11) cDNA(11) Primer pair(2)
Microarray probesets(8)
Other database
links
Ensembl Gene ModelENSMUSG00000015709 (Evidence)
Entrez Gene11864 (Evidence)
DFCITC1580410, TC1597503, TC1697164
DoTSDT.101381670, DT.101381674, DT.524165, DT.55269792
NIA Mouse Gene IndexU028811
International Mouse Knockout Project StatusArnt2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 11864 NCBI Gene Model | MGI Sequence Detail 115396 C57BL/6J ±  kb
transcript NM_007488 RefSeq | MGI Sequence Detail 6073 C57BL/6 
polypeptide Q61324 UniProt | EBI | MGI Sequence Detail 712 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(2) UniProt(1)
Polymorphisms SNPs(814 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
InterPro IPR001067 Nuclear translocator
InterPro IPR001610 PAC motif
InterPro IPR000014 PAS domain
InterPro IPR013767 PAS fold
InterPro IPR013655 PAS fold-3
Protein Ontology PR:000004304 aryl hydrocarbon receptor nuclear translocator 2
Graphical View of Protein Domain Structure
References (Earliest) J:31945 Hirose K, et al., cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt). Mol Cell Biol. 1996 Apr;16(4):1706-13
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(52)
Other
accession IDs 		MGD-MRK-35649
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/05/2013
MGI 5.13 		The Jackson Laboratory