About   Help   FAQ
Il15
Gene Detail
 Symbol
Name
ID
Il15
interleukin 15
MGI:103014
Feature Type protein coding gene
Genetic Map
Chromosome 8
39.33 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr8:82331624-82402586 bp, - strand
From NCBI annotation of GRCm38

  70963 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:487  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Protein SuperFamily: interleukin-15
Gene Tree: Il15
Human
homologs
Human Homolog IL15, interleukin 15
NCBI Gene ID 3600
neXtProt AC  NX_P40933
Human Synonyms  IL-15
Human Chr (Location)  4q31; chr4:142557749-142655140 (+)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(3) : Targeted(2) Chemically induced(1)
 
Mice homozygous for disruptions of this gene have normal life spans but display a variety of immune system abnormalities and maternal placental defects.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (26 annotations)
Process cell maturation, extrathymic T cell selection, ...
Component cell surface, cytoplasm, ...
Function cytokine activity, cytokine receptor binding
External Resources: FuncBase
Expression Literature Summary: (6 records)
Data Summary: Results (26)    Tissues (18)   
Theiler Stages: 19, 20, 21, 22, 23, 24, 25, 26
Assay TypeResults
RT-PCR 26
cDNA source data(16)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(23) Genomic(6) cDNA(16) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000031712 (Evidence)
Entrez Gene16168 (Evidence)
UniGene4392
DFCITC1583946, TC1591681, TC1620575
DoTSDT.110871937, DT.40135593, DT.94231639, DT.97358040
NIA Mouse Gene IndexU030010, U066722
PDB2PSM
Consensus CDS ProjectCCDS40401.1
International Mouse Knockout Project StatusIl15
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 16168 NCBI Gene Model | MGI Sequence Detail 70963 C57BL/6J ±  kb
transcript NM_008357 RefSeq | MGI Sequence Detail 1297 C57BL/6 
polypeptide P48346 UniProt | EBI | MGI Sequence Detail 162 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(4) UniProt(5)
Polymorphisms RFLP(2) : SNPs(286 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR020439 Interleukin-15
InterPro IPR003443 Interleukin-15-like
InterPro IPR020466 Interleukin-15, mammal
Protein Ontology PR:000001373 interleukin-15
Graphical View of Protein Domain Structure
References (Earliest) J:23246 Anderson DM, et al., Chromosomal assignment and genomic structure of Il15. Genomics. 1995 Feb 10;25(3):701-6
(Latest) J:195515 Lin GH, et al., GITR-Dependent Regulation of 4-1BB Expression: Implications for T Cell Memory and Anti-4-1BB-Induced Pathology. J Immunol. 2013 May 1;190(9):4627-39
All references(249)
Other
accession IDs 		MGD-MRK-23851, MGI:2142577
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
05/22/2013
MGI 5.13 		The Jackson Laboratory