About   Help   FAQ
Wnt11
Gene Detail
 Symbol
Name
ID
Wnt11
wingless-related MMTV integration site 11
MGI:101948
Feature Type protein coding gene
Genetic Map
Chromosome 7
53.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(14)
Sequence Map
Chr7:98835112-98855195 bp, + strand
From VEGA annotation of GRCm38

  20084 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:20970  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: int-1 transforming protein
Gene Tree: Wnt11
Human
homologs
Human Homolog WNT11, wingless-type MMTV integration site family, member 11
NCBI Gene ID 7481
neXtProt AC  NX_O96014
Human Synonyms  HWNT11
Human Chr (Location)  11q13.5; chr11:75897370-75917574 (-)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(6) : Targeted(6)
 
Homozygous mutation of this gene results in extensive embryonic lethality and mutants surviving to birth die within the first 2 days of life. The kidneys are small and exhibit delayed development.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (54 annotations)
Process artery morphogenesis, bone mineralization, ...
Component cytoplasm, extracellular matrix, ...
Function frizzled binding, protein binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression Literature Summary: (134 records)
Data Summary: Results (490)    Tissues (363)    Images (126)
Theiler Stages: 1, 2, 3, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14, 15, 17, 18, 19, 20, 21, 22, 23, 24, 26, 28
Assay TypeResults
Immunohistochemistry 6
RNA in situ 394
RT-PCR 88
RNase protection 2
cDNA source data(22)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(43) cDNA(24) Primer pair(13) Other(6)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000036052 (Evidence)
Ensembl Gene ModelENSMUSG00000015957 (Evidence)
Entrez Gene22411 (Evidence)
UniGene22182
DFCITC1587635, TC1597606
DoTSDT.40147241, DT.94230101
NIA Mouse Gene IndexU008431
Consensus CDS ProjectCCDS21475.1
International Mouse Knockout Project StatusWnt11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036052 VEGA Gene Model | MGI Sequence Detail 20084 C57BL/6J ±  kb
transcript OTTMUST00000092561 VEGA | MGI Sequence Detail 3451 Not Applicable 
polypeptide OTTMUSP00000051187 VEGA | MGI Sequence Detail 354 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(2) UniProt(6)
Polymorphisms RFLP(1) : SNPs(95 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR005817 Wnt
InterPro IPR026536 Wnt-11 protein
InterPro IPR018161 Wnt protein, conserved site
Protein Ontology PR:000017438 protein Wnt-11
References (Earliest) J:21464 Adamson MC, et al., Isolation and genetic mapping of two novel members of the murine Wnt gene family, Wnt11 and Wnt12, and the mapping of Wnt5a and Wnt7a. Genomics. 1994 Nov 1;24(1):9-13
(Latest) J:193842 Lu C, et al., Wnt-mediated reciprocal regulation between cartilage and bone development during endochondral ossification. Bone. 2013 Apr;53(2):566-74
All references(180)
Other
accession IDs 		MGD-MRK-18782
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
05/22/2013
MGI 5.13 		The Jackson Laboratory