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Htr1f
Gene Detail
 Symbol
Name
ID
Htr1f
5-hydroxytryptamine (serotonin) receptor 1F
MGI:99842
Synonyms Htr1eb
Feature Type protein coding gene
Genetic Map
Chromosome 16
37.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr16:64924729-65105784 bp, - strand
From NCBI annotation of GRCm38

  181056 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:37361  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: 5-hydroxytryptamine receptor 1
Gene Tree: Htr1f
Human
homologs
Human Homolog HTR1F, 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
NCBI Gene ID 3355
neXtProt AC  NX_P30939
Human Synonyms  5-HT1F, 5-HT-1F, 5HT6, HTR1EL, MR77
Human Chr (Location)  3p12; chr3:88031726-88042919 (+)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(2) : Targeted(2)
 
Mice homozygous for disruptions in this gene display decreased temperature sensitivity and physiological abnormalities in nerve fibers.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (15 annotations)
Process G-protein coupled receptor signaling pathway, serotonin receptor signaling pathway, ...
Component integral to membrane, integral to plasma membrane, ...
Function G-protein coupled receptor activity, serotonin binding, ...
External Resources: FuncBase
Expression Literature Summary: (4 records)
Data Summary: Results (280)    Tissues (97)    Images (37)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 43
In situ reporter (knock in) 61
RT-PCR 176
cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(9) cDNA(6) Primer pair(3)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000050783 (Evidence)
Entrez Gene15557 (Evidence)
UniGene5040
DFCITC1589072
DoTSDT.91335485
NIA Mouse Gene IndexU037178
Consensus CDS ProjectCCDS28267.1
International Mouse Knockout Project StatusHtr1f
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 15557 NCBI Gene Model | MGI Sequence Detail 181056 C57BL/6J ±  kb
transcript NM_008310 RefSeq | MGI Sequence Detail 2509 C57BL/6 
polypeptide Q02284 UniProt | EBI | MGI Sequence Detail 366 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2) UniProt(2)
Polymorphisms RFLP(1) : SNPs(600 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR000450 5-Hydroxytryptamine 1F receptor
InterPro IPR002231 5-Hydroxytryptamine receptor family
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001165 5-hydroxytryptamine receptor 1F
Graphical View of Protein Domain Structure
References (Earliest) J:2640 Amlaiky N, et al., Isolation of a mouse 5HT1E-like serotonin receptor expressed predominantly in hippocampus. J Biol Chem. 1992 Oct 5;267(28):19761-4
(Latest) J:194270 Guadiana SM, et al., Arborization of dendrites by developing neocortical neurons is dependent on primary cilia and type 3 adenylyl cyclase. J Neurosci. 2013 Feb 6;33(6):2626-38
All references(34)
Other
accession IDs 		MGD-MRK-11006, MGD-MRK-16633, MGI:96280
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/05/2013
MGI 5.13 		The Jackson Laboratory