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Thy1
Gene Detail
 Symbol
Name
ID
Thy1
thymus cell antigen 1, theta
MGI:98747
STS D9Nds3
Synonyms CD90, T25, theta, Thy-1, Thy1.1, Thy 1.2, Thy-1.2, Thy1.2
Feature Type protein coding gene
Genetic Map
Chromosome 9
24.52 cM
Detailed Genetic Map ± 1 cM


Mapping data(55)
Sequence Map
Chr9:44043384-44048579 bp, + strand
From VEGA annotation of GRCm38

  5196 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:4580  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: Thy-1 membrane glycoprotein
Gene Tree: Thy1
Human
homologs
Human Homolog THY1, Thy-1 cell surface antigen
NCBI Gene ID 7070
neXtProt AC  NX_P04216
Human Synonyms  CD90
Human Chr (Location)  11q23.3; chr11:119288655-119294246 (-)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(7) : Targeted(4) Gene trapped(1) Other(2)
 
Homozygous null mice are viable, fertile, and display no abnormalities in the brain and spinal cord, have normal axonal development and regeneration and no behavioral abnormalities. Long term potentiation is inhibited in the dentate gyrus.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (32 annotations)
Process angiogenesis, cell-cell adhesion, ...
Component anchored to external side of plasma membrane, anchored to membrane, ...
Function enzyme binding, GPI anchor binding, ...
External Resources: FuncBase
Expression Literature Summary: (27 records)
Data Summary: Results (198)    Tissues (40)    Images (61)
Theiler Stages: 20, 22, 23, 24, 26, 28
Assay TypeResults
Immunohistochemistry 8
RNA in situ 175
RT-PCR 15
cDNA source data(54)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(82) Genomic(18) cDNA(57) Primer pair(6) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000016734 (Evidence)
Ensembl Gene ModelENSMUSG00000032011 (Evidence)
Entrez Gene21838 (Evidence)
UniGene3951
DFCITC1577066, TC1628688, TC1715283
DoTSDT.101337538, DT.533681, DT.94314670
Consensus CDS ProjectCCDS23093.1
International Mouse Knockout Project StatusThy1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016734 VEGA Gene Model | MGI Sequence Detail 5196 C57BL/6J ±  kb
transcript OTTMUST00000040558 VEGA | MGI Sequence Detail 1735 Not Applicable 
polypeptide OTTMUSP00000018127 VEGA | MGI Sequence Detail 162 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(2) UniProt(2)
Polymorphisms All PCR and RFLP(8) : PCR(2) RFLP(6) SNPs(72 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR013151 Immunoglobulin
InterPro IPR007110 Immunoglobulin-like
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003596 Immunoglobulin V-set, subgroup
Protein Ontology PR:000001843 Thy-1 membrane glycoprotein
References (Earliest) J:24839 REIF AE, et al., THE AKR THYMIC ANTIGEN AND ITS DISTRIBUTION IN LEUKEMIAS AND NERVOUS TISSUES. J Exp Med. 1964 Sep 1;120:413-33
(Latest) J:193313 Takase HM, et al., FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration. Genes Dev. 2013 Jan 15;27(2):169-81
All references(181)
Other
accession IDs 		MGD-MRK-15100, MGD-MRK-15102
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory