About   Help   FAQ
Os Gene Detail
Summary
  • Symbol
    Os
  • Name
    oligosyndactylism
  • Synonyms
    94-A, 94-K, PlmTgN(Pgk1)1Ddp, PlmTgN(Pgk1)2Ddp
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:97446
    NCBI Gene: 109678
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 8, Syntenic
  • Mapping Data
    39 experiments
Strain
Comparison
more
  • RFLP
    2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    34 phenotypes from 1 allele in 4 genetic backgrounds
    1 images
    31 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutations in this gene result in heterozygous mice with limb and kidney abnormalities. The homozygote dies soon after implantation.
Expression
less
  • cDNA Data
    1
Sequences &
Gene Models
less
Molecular
Reagents
less
  • All nucleic 10
    Genomic 9
    cDNA 1
Other
Accession IDs
less
MGD-MRK-13054, MGI:892015, MGI:892016
References
more
  • Summaries
    All 60
    Phenotypes 31
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
  • Latest
    J:282477 Baldelomar EJ, et al., In vivo measurements of kidney glomerular number and size in healthy and Os(/+) mice using MRI. Am J Physiol Renal Physiol. 2019 Oct 1;317(4):F865-F873
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory