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Jund
Gene Detail
 Symbol
Name
ID
Jund
Jun proto-oncogene related gene d
MGI:96648
Feature Type protein coding gene
Genetic Map
Chromosome 8
34.15 cM, cytoband C2
Detailed Genetic Map ± 1 cM


Mapping data(23)
Sequence Map
Chr8:70697739-70700616 bp, + strand
From NCBI annotation of GRCm38

  2878 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:3910  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: transcription factor AP-1
Gene Tree: Jund
Human
homologs
Human Homolog JUND, jun D proto-oncogene
NCBI Gene ID 3727
neXtProt AC  NX_P17535
Human Synonyms  AP-1
Human Chr (Location)  19p13.2; chr19:18390563-18392432 (-)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(5) : Targeted(1) Gene trapped(4)
 
Homozygotes show reduced growth, sensitivity to LPS-induced hepatitis, and male infertility due to hormonal imbalance and impaired spermatogenesis. Targeted cells and mice are sensitive to p53-dependent stress and TNF-induced apoptosis, and show aberrant T cell proliferation and Th2 differentiation.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (15 annotations)
Process cellular response to calcium ion, osteoblast development, ...
Component nucleus, protein complex
Function DNA binding, double-stranded DNA binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression Literature Summary: (8 records)
Data Summary: Results (169)    Tissues (168)    Images (13)
Theiler Stages: 17, 18, 21, 22, 23, 28
Assay TypeResults
RNA in situ 123
RT-PCR 46
cDNA source data(14)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(19) Genomic(1) cDNA(15) Primer pair(2) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000071076 (Evidence)
Entrez Gene16478 (Evidence)
DFCITC1575686, TC1596368
NIA Mouse Gene IndexU009438
Consensus CDS ProjectCCDS40375.1
International Mouse Knockout Project StatusJund
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 16478 NCBI Gene Model | MGI Sequence Detail 2878 C57BL/6J ±  kb
transcript NM_010592 RefSeq | MGI Sequence Detail 2878 Not Specified 
polypeptide P15066 UniProt | EBI | MGI Sequence Detail 341 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(2)
Polymorphisms RFLP(4) : SNPs(13 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR004827 Basic-leucine zipper domain
InterPro IPR008917 Eukaryotic transcription factor, Skn-1-like, DNA-binding
InterPro IPR005643 Jun-like transcription factor
InterPro IPR002112 Transcription factor Jun
Protein Ontology PR:000009234 transcription factor jun-D
Graphical View of Protein Domain Structure
References (Earliest) J:9466 Nakabeppu Y, et al., DNA binding activities of three murine Jun proteins: stimulation by Fos. Cell. 1988 Dec 2;55(5):907-15
(Latest) J:194035 Kan A, et al., c-Jun is required for the specification of joint cell fates. Genes Dev. 2013 Mar 1;27(5):514-24
All references(85)
Other
accession IDs 		MGD-MRK-11541, MGD-MRK-11542
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory