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Il9
Gene Detail
 Symbol
Name
ID
Il9
interleukin 9
MGI:96563
STS D13Mit13
Synonyms Il-9, P40
Feature Type protein coding gene
Genetic Map
Chromosome 13
30.06 cM
Detailed Genetic Map ± 1 cM


Mapping data(48)
Sequence Map
Chr13:56479277-56482246 bp, - strand
From NCBI annotation of GRCm38

  2970 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology 		HomoloGene:492  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: interleukin-9
Gene Tree: Il9
Human
homologs
Human Homolog IL9, interleukin 9
NCBI Gene ID 3578
neXtProt AC  NX_P15248
Human Synonyms  HP40, IL-9, P40
Human Chr (Location)  5q31.1; chr5:135227935-135231516 (-)  GRCh37.p10
Alleles
and
phenotypes 		All alleles(2) : Targeted(2)
 
Homozygous null mice are viable and show no overt phenotype, however when challenged, aspects of the inflammatory response are shown to be impaired.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (11 annotations)
Process immune response, positive regulation of cell growth, ...
Component extracellular region, extracellular space
Function cytokine activity, cytokine receptor binding, ...
External Resources: FuncBase
Expression Literature Summary: (4 records)
Data Summary: Results (27)    Tissues (21)   
Theiler Stages: 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
RT-PCR 27
cDNA source data(1)
External Resources: GEO   ArrayExpress
Molecular
reagents 		All nucleic(5) Genomic(1) cDNA(1) Primer pair(1) Other(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000021538 (Evidence)
Entrez Gene16198 (Evidence)
UniGene3006
DFCITC1595383
DoTSDT.91443870
NIA Mouse Gene IndexU034833
Consensus CDS ProjectCCDS26562.1
International Mouse Knockout Project StatusIl9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 16198 NCBI Gene Model | MGI Sequence Detail 2970 C57BL/6J ±  kb
transcript NM_008373 RefSeq | MGI Sequence Detail 536 C57BL/6 
polypeptide P15247 UniProt | EBI | MGI Sequence Detail 144 Not Applicable 

For the selected sequences
All sequences(14) RefSeq(2) UniProt(1)
Polymorphisms RFLP(4) : SNPs(46 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR018049 Interleukin-7/-9, conserved site
InterPro IPR000226 Interleukin-7/interleukin-9
InterPro IPR020447 Interleukin-9
Protein Ontology PR:000001396 interleukin-9
Graphical View of Protein Domain Structure
References (Earliest) J:14595 Uyttenhove C, et al., Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity. Proc Natl Acad Sci U S A. 1988 Sep;85(18):6934-8
(Latest) J:182002 Ahrens R, et al., Intestinal mast cell levels control severity of oral antigen-induced anaphylaxis in mice. Am J Pathol. 2012 Apr;180(4):1535-46
All references(98)
Other
accession IDs 		MGD-MRK-11359, MGD-MRK-11397
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory