GO Annotations Graph

• Symbol: Ighmbp2
• Name: immunoglobulin mu DNA binding protein 2
• ID: MGI:99954

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043139	5'-3' DNA helicase activity	ISO	J:164563
Molecular Function	GO:0043139	5'-3' DNA helicase activity	IBA	J:265628
Molecular Function	GO:0032574	5'-3' RNA helicase activity	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	IDA	J:314557
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	ISO	J:164563
Molecular Function	GO:0008186	ATP-dependent activity, acting on RNA	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:155856
Molecular Function	GO:0036121	double-stranded DNA helicase activity	ISO	J:164563
Molecular Function	GO:1990955	G-rich single-stranded DNA binding	IDA	J:4973
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0004386	helicase activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:148546
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0043022	ribosome binding	IDA	J:146154
Molecular Function	GO:0043022	ribosome binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0003724	RNA helicase activity	IEA	J:72245
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003727	single-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0003727	single-stranded RNA binding	IDA	J:314557
Molecular Function	GO:0008134	transcription factor binding	ISO	J:164563
Molecular Function	GO:0000049	tRNA binding	ISO	J:164563
Molecular Function	GO:0000049	tRNA binding	ISO	J:148546
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0030424	axon	IDA	J:146154
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:148546
Cellular Component	GO:0030426	growth cone	IDA	J:146154
Cellular Component	GO:0043025	neuronal cell body	IDA	J:92862
Cellular Component	GO:0043025	neuronal cell body	IDA	J:92862
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:148546
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:146154
Cellular Component	GO:1990904	ribonucleoprotein complex	IDA	J:146154
Biological Process	GO:0032508	DNA duplex unwinding	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:91301
Biological Process	GO:0050905	neuromuscular process	IMP	J:99795
Biological Process	GO:0010501	RNA secondary structure unwinding	ISO	J:164563
Biological Process	GO:0021522	spinal cord motor neuron differentiation	IMP	J:148546
Biological Process	GO:0006412	translation	NAS	J:148546