GO Annotations Graph

• Symbol: Slc1a3
• Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3
• ID: MGI:99917

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015172	acidic amino acid transmembrane transporter activity	IMP	J:241032
Molecular Function	GO:0016597	amino acid binding	IDA	J:16962
Molecular Function	GO:0016595	glutamate binding	IDA	J:16962
Molecular Function	GO:0015501	glutamate:sodium symporter activity	ISO	J:164563
Molecular Function	GO:0015501	glutamate:sodium symporter activity	ISO	J:155856
Molecular Function	GO:0015501	glutamate:sodium symporter activity	IBA	J:265628
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	IDA	J:89770
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	IDA	J:16962
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	IMP	J:104910
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:89770
Molecular Function	GO:0015293	symporter activity	IEA	J:72247
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Cellular Component	GO:0009925	basal plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0071944	cell periphery	IDA	J:162095
Cellular Component	GO:0042995	cell projection	IDA	J:85573
Cellular Component	GO:0042995	cell projection	IDA	J:99826
Cellular Component	GO:0042995	cell projection	IDA	J:89770
Cellular Component	GO:0042995	cell projection	IDA	J:48808
Cellular Component	GO:0009986	cell surface	IDA	J:89770
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0098796	membrane protein complex	ISO	J:155856
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IDA	J:162095
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IDA	J:67408
Cellular Component	GO:0043025	neuronal cell body	IDA	J:99826
Cellular Component	GO:0043025	neuronal cell body	IDA	J:85573
Cellular Component	GO:0043025	neuronal cell body	IDA	J:44290
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:241032
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	TAS	J:297342
Cellular Component	GO:0005886	plasma membrane	IDA	J:89770
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:297467
Biological Process	GO:0006865	amino acid transport	IEA	J:60000
Biological Process	GO:0031223	auditory behavior	IMP	J:66146
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	IMP	J:46746
Biological Process	GO:0071314	cellular response to cocaine	IDA	J:299319
Biological Process	GO:1902476	chloride transmembrane transport	ISO	J:164563
Biological Process	GO:0021545	cranial nerve development	IMP	J:46746
Biological Process	GO:0070779	D-aspartate import across plasma membrane	ISO	J:164563
Biological Process	GO:0070779	D-aspartate import across plasma membrane	IMP	J:241032
Biological Process	GO:0070779	D-aspartate import across plasma membrane	IBA	J:265628
Biological Process	GO:0009449	gamma-aminobutyric acid biosynthetic process	IMP	J:104928
Biological Process	GO:0006883	intracellular sodium ion homeostasis	IMP	J:155496
Biological Process	GO:0140009	L-aspartate import across plasma membrane	ISO	J:164563
Biological Process	GO:0140009	L-aspartate import across plasma membrane	ISO	J:155856
Biological Process	GO:0140009	L-aspartate import across plasma membrane	IBA	J:265628
Biological Process	GO:0051938	L-glutamate import	ISO	J:164563
Biological Process	GO:0051938	L-glutamate import	IMP	J:104910
Biological Process	GO:0098712	L-glutamate import across plasma membrane	ISO	J:155856
Biological Process	GO:0098712	L-glutamate import across plasma membrane	ISO	J:164563
Biological Process	GO:0098712	L-glutamate import across plasma membrane	IBA	J:265628
Biological Process	GO:0098712	L-glutamate import across plasma membrane	IMP	J:96918
Biological Process	GO:0098712	L-glutamate import across plasma membrane	IMP	J:155496
Biological Process	GO:0015813	L-glutamate transmembrane transport	ISO	J:164563
Biological Process	GO:0015813	L-glutamate transmembrane transport	ISO	J:155856
Biological Process	GO:0015813	L-glutamate transmembrane transport	IDA	J:89770
Biological Process	GO:0015813	L-glutamate transmembrane transport	ISO	J:22673
Biological Process	GO:0015813	L-glutamate transmembrane transport	ISO	J:22673
Biological Process	GO:0043490	malate-aspartate shuttle	ISO	J:155856
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:46746
Biological Process	GO:0050806	positive regulation of synaptic transmission	IMP	J:47463
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0043200	response to amino acid	ISO	J:22673
Biological Process	GO:0046677	response to antibiotic	IMP	J:99715
Biological Process	GO:0010035	response to inorganic substance	ISO	J:22673
Biological Process	GO:0010035	response to inorganic substance	ISO	J:22673
Biological Process	GO:0009416	response to light stimulus	IMP	J:47463
Biological Process	GO:0009611	response to wounding	IMP	J:46746
Biological Process	GO:0009410	response to xenobiotic stimulus	IMP	J:47463
Biological Process	GO:0007605	sensory perception of sound	IMP	J:66146