GO Annotations Graph

• Symbol: Cebpa
• Name: CCAAT/enhancer binding protein alpha
• ID: MGI:99480

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:188795
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:272999
Molecular Function	GO:0003677	DNA binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	IDA	J:92958
Molecular Function	GO:0003677	DNA binding	IDA	J:64814
Molecular Function	GO:0003677	DNA binding	IDA	J:111670
Molecular Function	GO:0003677	DNA binding	IDA	J:121854
Molecular Function	GO:0003677	DNA binding	IDA	J:85421
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:117723
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:210944
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	NAS	J:114121
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:121854
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:64004
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:155856
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:120098
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:155856
Molecular Function	GO:0071837	HMG box domain binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:85421
Molecular Function	GO:0019900	kinase binding	IPI	J:219103
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:219103
Molecular Function	GO:0005515	protein binding	IPI	J:152000
Molecular Function	GO:0005515	protein binding	IPI	J:236647
Molecular Function	GO:0005515	protein binding	IPI	J:124079
Molecular Function	GO:0005515	protein binding	IPI	J:237490
Molecular Function	GO:0005515	protein binding	IPI	J:53930
Molecular Function	GO:0005515	protein binding	IPI	J:141842
Molecular Function	GO:0005515	protein binding	IPI	J:53930
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:155856
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:210944
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:72330
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0097677	STAT family protein binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:141842
Molecular Function	GO:0008134	transcription factor binding	IPI	J:117723
Cellular Component	GO:1990647	C/EBP complex	ISO	J:164563
Cellular Component	GO:0036488	CHOP-C/EBP complex	ISO	J:155856
Cellular Component	GO:0036488	CHOP-C/EBP complex	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016363	nuclear matrix	ISO	J:155856
Cellular Component	GO:0005730	nucleolus	ISO	J:155856
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-442497
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9616215
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9616883
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9617077
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9625589
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9626284
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:72330
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	NAS	J:320139
Cellular Component	GO:0005634	nucleus	IDA	J:76945
Cellular Component	GO:0005634	nucleus	IDA	J:95079
Cellular Component	GO:0005634	nucleus	IDA	J:92958
Cellular Component	GO:0005634	nucleus	IDA	J:175461
Cellular Component	GO:0005634	nucleus	IDA	J:95079
Cellular Component	GO:0005634	nucleus	IDA	J:95079
Cellular Component	GO:0005634	nucleus	IDA	J:143315
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0035189	Rb-E2F complex	ISO	J:155856
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:155856
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:84580
Biological Process	GO:0050873	brown fat cell differentiation	IDA	J:137608
Biological Process	GO:0008283	cell population proliferation	IMP	J:92958
Biological Process	GO:0071285	cellular response to lithium ion	IDA	J:99298
Biological Process	GO:0071407	cellular response to organic cyclic compound	IDA	J:78619
Biological Process	GO:0071356	cellular response to tumor necrosis factor	IDA	J:1388
Biological Process	GO:0008203	cholesterol metabolic process	IMP	J:149088
Biological Process	GO:0019221	cytokine-mediated signaling pathway	NAS	J:114121
Biological Process	GO:0001892	embryonic placenta development	IGI	J:94195
Biological Process	GO:0002070	epithelial cell maturation	IMP	J:106543
Biological Process	GO:0002070	epithelial cell maturation	IMP	J:106543
Biological Process	GO:0045444	fat cell differentiation	IMP	J:218372
Biological Process	GO:0045444	fat cell differentiation	IDA	J:72330
Biological Process	GO:0045444	fat cell differentiation	ISO	J:155856
Biological Process	GO:0045444	fat cell differentiation	IDA	J:81172
Biological Process	GO:0045444	fat cell differentiation	IDA	J:76817
Biological Process	GO:0042593	glucose homeostasis	IMP	J:35795
Biological Process	GO:0042593	glucose homeostasis	IMP	J:120098
Biological Process	GO:0030851	granulocyte differentiation	IDA	J:72330
Biological Process	GO:0030851	granulocyte differentiation	IMP	J:94682
Biological Process	GO:0071425	hematopoietic stem cell proliferation	IMP	J:92958
Biological Process	GO:0048839	inner ear development	IDA	J:174607
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0055088	lipid homeostasis	IMP	J:120098
Biological Process	GO:0001889	liver development	IMP	J:35795
Biological Process	GO:0001889	liver development	IMP	J:114400
Biological Process	GO:0030324	lung development	IMP	J:35795
Biological Process	GO:0030324	lung development	IMP	J:106543
Biological Process	GO:0030324	lung development	IMP	J:106543
Biological Process	GO:0030225	macrophage differentiation	IMP	J:92958
Biological Process	GO:0007005	mitochondrion organization	IMP	J:76945
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0030099	myeloid cell differentiation	IDA	J:114121
Biological Process	GO:0030099	myeloid cell differentiation	IBA	J:265628
Biological Process	GO:0045786	negative regulation of cell cycle	IDA	J:219103
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	IDA	J:72330
Biological Process	GO:0008285	negative regulation of cell population proliferation	IDA	J:219106
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:72330
Biological Process	GO:1902034	negative regulation of hematopoietic stem cell proliferation	IMP	J:92958
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:64004
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:218171
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:121854
Biological Process	GO:2000144	positive regulation of DNA-templated transcription initiation	ISO	J:164563
Biological Process	GO:0045600	positive regulation of fat cell differentiation	ISO	J:155856
Biological Process	GO:0045600	positive regulation of fat cell differentiation	IDA	J:125420
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:282599
Biological Process	GO:0050729	positive regulation of inflammatory response	IMP	J:263417
Biological Process	GO:0043032	positive regulation of macrophage activation	IMP	J:263417
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IDA	J:91833
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:210944
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:141842
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:21626
Biological Process	GO:0042127	regulation of cell population proliferation	IMP	J:114400
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	NAS	J:114121
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:53590
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:117723
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:141842
Biological Process	GO:0006360	transcription by RNA polymerase I	ISO	J:164563
Biological Process	GO:0000050	urea cycle	IDA	J:121854
Biological Process	GO:0050872	white fat cell differentiation	IMP	J:89611
Biological Process	GO:0050872	white fat cell differentiation	IMP	J:89611