GO Annotations Graph

• Symbol: Yes1
• Name: YES proto-oncogene 1, Src family tyrosine kinase
• ID: MGI:99147

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0005154	epidermal growth factor receptor binding	ISO	J:155856
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0001784	phosphotyrosine residue binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:72781
Molecular Function	GO:0005515	protein binding	IPI	J:182976
Molecular Function	GO:0005515	protein binding	IPI	J:72781
Molecular Function	GO:0005515	protein binding	IPI	J:72781
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:155856
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0004713	protein tyrosine kinase activity	IDA	J:236752
Molecular Function	GO:0004713	protein tyrosine kinase activity	TAS	Reactome:R-MMU-9763891
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Cellular Component	GO:0005884	actin filament	IDA	J:125001
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9680646
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9680706
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9682158
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9682182
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9682572
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9763891
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9763892
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9763903
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9764150
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9817994
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9818009
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:125001
Cellular Component	GO:0099091	postsynaptic specialization, intracellular component	ISO	J:155856
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	IDA	J:125001
Biological Process	GO:0071300	cellular response to retinoic acid	IDA	J:182976
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	IGI	J:176254
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	IGI	J:176254
Biological Process	GO:0045087	innate immune response	IBA	J:265628
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IDA	J:182976
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:182976
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:182976
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:182976
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0010827	regulation of glucose transmembrane transport	IDA	J:72781
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628