GO Annotations Graph

• Symbol: Syp
• Name: synaptophysin
• ID: MGI:98467

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015485	cholesterol binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:140969
Molecular Function	GO:0005515	protein binding	IPI	J:140969
Molecular Function	GO:0005515	protein binding	IPI	J:140969
Molecular Function	GO:0005515	protein binding	IPI	J:140969
Molecular Function	GO:0005515	protein binding	IPI	J:140969
Molecular Function	GO:0005515	protein binding	IPI	J:140969
Molecular Function	GO:0005515	protein binding	IPI	J:140969
Molecular Function	GO:0005515	protein binding	IPI	J:140969
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0042169	SH2 domain binding	IDA	J:140969
Molecular Function	GO:0000149	SNARE binding	ISO	J:155856
Molecular Function	GO:0017075	syntaxin-1 binding	ISO	J:29256
Cellular Component	GO:0060203	clathrin-sculpted glutamate transport vesicle membrane	TAS	Reactome:R-MMU-9664156
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	IDA	J:113153
Cellular Component	GO:0043229	intracellular organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:96798
Cellular Component	GO:0016020	membrane	IDA	J:140969
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:164294
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IMP	J:175650
Cellular Component	GO:0043005	neuron projection	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	IDA	J:169453
Cellular Component	GO:0044306	neuron projection terminus	ISO	J:155856
Cellular Component	GO:0044306	neuron projection terminus	IDA	J:101575
Cellular Component	GO:0044306	neuron projection terminus	IDA	J:77234
Cellular Component	GO:0044309	neuron spine	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:116082
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0098793	presynapse	IDA	J:282820
Cellular Component	GO:0048786	presynaptic active zone	IDA	J:175650
Cellular Component	GO:0048786	presynaptic active zone	IBA	J:265628
Cellular Component	GO:0048786	presynaptic active zone	ISO	J:120748
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:154140
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:92443
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:58559
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:58559
Cellular Component	GO:0045202	synapse	IDA	J:81738
Cellular Component	GO:0045202	synapse	IDA	J:86623
Cellular Component	GO:0045202	synapse	IDA	J:201575
Cellular Component	GO:0045202	synapse	IDA	J:140969
Cellular Component	GO:0045202	synapse	IDA	J:114833
Cellular Component	GO:0045202	synapse	IDA	J:79322
Cellular Component	GO:0045202	synapse	IDA	J:76455
Cellular Component	GO:0045202	synapse	IDA	J:125344
Cellular Component	GO:0045202	synapse	IDA	J:199579
Cellular Component	GO:0045202	synapse	IDA	J:140969
Cellular Component	GO:0045202	synapse	IDA	J:116055
Cellular Component	GO:0045202	synapse	IDA	J:140969
Cellular Component	GO:0045202	synapse	IDA	J:132267
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:104925
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:178379
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:44290
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:86727
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:125904
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:75306
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:78720
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	IBA	J:265628
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:260353
Cellular Component	GO:0030672	synaptic vesicle membrane	TAS	J:79361
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:83886
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:90137
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	IDA	J:258726
Cellular Component	GO:0043195	terminal bouton	IDA	J:218588
Biological Process	GO:0071310	cellular response to organic substance	IDA	J:137727
Biological Process	GO:0007268	chemical synaptic transmission	TAS	J:79361
Biological Process	GO:0006897	endocytosis	ISO	J:155856
Biological Process	GO:0006897	endocytosis	TAS	J:79361
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	IMP	J:58559
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	IBA	J:265628
Biological Process	GO:2000474	regulation of opioid receptor signaling pathway	ISO	J:155856
Biological Process	GO:0048172	regulation of short-term neuronal synaptic plasticity	IMP	J:58559
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IMP	J:58559
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IDA	J:58559
Biological Process	GO:0048488	synaptic vesicle endocytosis	IMP	J:174969