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GO Annotations Graph
Symbol
Name
ID
Sos1
SOS Ras/Rac guanine nucleotide exchange factor 1
MGI:98354

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003677DNA bindingIEAJ:72247
Molecular FunctionGO:0005085guanyl-nucleotide exchange factor activityIEAJ:60000
Molecular FunctionGO:0005085guanyl-nucleotide exchange factor activityIEAJ:72247
Molecular FunctionGO:0005515protein bindingIPIJ:40779
Molecular FunctionGO:0005515protein bindingIPIJ:31423
Molecular FunctionGO:0005515protein bindingIPIJ:105250
Molecular FunctionGO:0005515protein bindingIPIJ:196125
Molecular FunctionGO:0005515protein bindingIPIJ:200311
Molecular FunctionGO:0005515protein bindingIPIJ:189787
Molecular FunctionGO:0005515protein bindingIPIJ:200364
Molecular FunctionGO:0005515protein bindingIPIJ:190009
Molecular FunctionGO:0005515protein bindingIPIJ:206901
Molecular FunctionGO:0005515protein bindingIPIJ:200431
Molecular FunctionGO:0005515protein bindingIPIJ:200318
Molecular FunctionGO:0005515protein bindingIPIJ:201945
Molecular FunctionGO:0046982protein heterodimerization activityIEAJ:72247
Molecular FunctionGO:0005088Ras guanyl-nucleotide exchange factor activityISOJ:164563
Molecular FunctionGO:0005088Ras guanyl-nucleotide exchange factor activityIMPJ:100216
Molecular FunctionGO:0005089Rho guanyl-nucleotide exchange factor activityIEAJ:72247
Molecular FunctionGO:0017124SH3 domain bindingISOJ:155856
Cellular ComponentGO:0043025neuronal cell bodyISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0014069postsynaptic densityISOJ:155856
Biological ProcessGO:0001782B cell homeostasisIGIJ:206090
Biological ProcessGO:0048514blood vessel morphogenesisIMPJ:38321
Biological ProcessGO:0003209cardiac atrium morphogenesisIMPJ:38321
Biological ProcessGO:0007173epidermal growth factor receptor signaling pathwayIMPJ:38321
Biological ProcessGO:0061029eyelid development in camera-type eyeIGIJ:38321
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIGIJ:73116
Biological ProcessGO:0001942hair follicle developmentIGIJ:38321
Biological ProcessGO:0003007heart morphogenesisIMPJ:38321
Biological ProcessGO:0061384heart trabecula morphogenesisIMPJ:38321
Biological ProcessGO:0002260lymphocyte homeostasisIGIJ:206090
Biological ProcessGO:1904693midbrain morphogenesisIMPJ:38321
Biological ProcessGO:0035264multicellular organism growthIMPJ:38321
Biological ProcessGO:0048011neurotrophin TRK receptor signaling pathwayISOJ:155856
Biological ProcessGO:0060021palate developmentIMPJ:38321
Biological ProcessGO:0003344pericardium morphogenesisIMPJ:38321
Biological ProcessGO:0043547positive regulation of GTPase activityISOJ:164563
Biological ProcessGO:0051057positive regulation of small GTPase mediated signal transductionISOJ:155856
Biological ProcessGO:0007265Ras protein signal transductionISOJ:155856
Biological ProcessGO:2000973regulation of pro-B cell differentiationIGIJ:206090
Biological ProcessGO:0035023regulation of Rho protein signal transductionIEAJ:72247
Biological ProcessGO:0033081regulation of T cell differentiation in thymusIGIJ:206090
Biological ProcessGO:0042129regulation of T cell proliferationIGIJ:206090
Biological ProcessGO:0007264small GTPase mediated signal transductionIMPJ:100216
Biological ProcessGO:0007296vitellogenesisIMPJ:38321


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory