Rxra GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Rxra
retinoid X receptor alpha
MGI:98214

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:264834
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:130306
Molecular Function	GO:0003677	DNA binding	IDA	J:96189
Molecular Function	GO:0003677	DNA binding	IDA	J:95384
Molecular Function	GO:0050692	DNA binding domain binding	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IGI	J:23077
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:73065
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IGI	J:23077
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:73065
Molecular Function	GO:0043167	ion binding	ISO	J:164563
Molecular Function	GO:0050693	LBD domain binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:154828
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:94471
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:2326
Molecular Function	GO:0016922	nuclear receptor binding	ISO	J:164563
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	ISO	J:155856
Molecular Function	GO:0003707	nuclear steroid receptor activity	IEA	J:72247
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	ISO	J:155856
Molecular Function	GO:0042809	nuclear vitamin D receptor binding	ISO	J:164563
Molecular Function	GO:0042277	peptide binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:178274
Molecular Function	GO:0005515	protein binding	IPI	J:30618
Molecular Function	GO:0005515	protein binding	IPI	J:81892
Molecular Function	GO:0005515	protein binding	IPI	J:37212
Molecular Function	GO:0005515	protein binding	IPI	J:48279
Molecular Function	GO:0005515	protein binding	IPI	J:114350
Molecular Function	GO:0005515	protein binding	IPI	J:178274
Molecular Function	GO:0005515	protein binding	IPI	J:156072
Molecular Function	GO:0005515	protein binding	IPI	J:236712
Molecular Function	GO:0005515	protein binding	IPI	J:236712
Molecular Function	GO:0005515	protein binding	IPI	J:56144
Molecular Function	GO:0005515	protein binding	IPI	J:105576
Molecular Function	GO:0005515	protein binding	IPI	J:141260
Molecular Function	GO:0005515	protein binding	IPI	J:114735
Molecular Function	GO:0005515	protein binding	IPI	J:125396
Molecular Function	GO:0005515	protein binding	IPI	J:114735
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0001972	retinoic acid binding	ISO	J:164563
Molecular Function	GO:0044323	retinoic acid-responsive element binding	ISO	J:164563
Molecular Function	GO:0044323	retinoic acid-responsive element binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:73065
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:94492
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IPI	J:96189
Molecular Function	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	IDA	J:78038
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:73065
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:22384
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:22384
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:154828
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0001223	transcription coactivator binding	IPI	J:178274
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:164563
Molecular Function	GO:0070644	vitamin D response element binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-442515
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-556760
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617960
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617990
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619411
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619434
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619441
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5693628
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:130306
Cellular Component	GO:0005634	nucleus	IDA	J:56144
Cellular Component	GO:0043235	receptor complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IDA	J:154828
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IDA	J:314644
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	EXP	J:320338
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	NAS	J:45674
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:314562
Cellular Component	GO:0005667	transcription regulator complex	EXP	J:320125
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Biological Process	GO:0048856	anatomical structure development	IBA	J:265628
Biological Process	GO:0060978	angiogenesis involved in coronary vascular morphogenesis	TAS	J:169941
Biological Process	GO:0043010	camera-type eye development	IGI	J:42773
Biological Process	GO:0055007	cardiac muscle cell differentiation	TAS	J:169941
Biological Process	GO:0060038	cardiac muscle cell proliferation	TAS	J:169941
Biological Process	GO:0060038	cardiac muscle cell proliferation	IMP	J:44836
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:44836
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:94471
Biological Process	GO:0007566	embryo implantation	IGI	J:52278
Biological Process	GO:0010467	gene expression	IMP	J:264834
Biological Process	GO:0007507	heart development	TAS	J:169941
Biological Process	GO:0007507	heart development	IMP	J:48085
Biological Process	GO:0003007	heart morphogenesis	TAS	J:169941
Biological Process	GO:0009755	hormone-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0001701	in utero embryonic development	IGI	J:52278
Biological Process	GO:0030522	intracellular receptor signaling pathway	IDA	J:94471
Biological Process	GO:0001893	maternal placenta development	IGI	J:52278
Biological Process	GO:0060485	mesenchyme development	TAS	J:169941
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	IDA	J:2326
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	NAS	J:45674
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	IDA	J:314644
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0010629	negative regulation of gene expression	TAS	J:169941
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:178114
Biological Process	GO:0035357	peroxisome proliferator activated receptor signaling pathway	ISO	J:164563
Biological Process	GO:0001890	placenta development	IMP	J:44230
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0030501	positive regulation of bone mineralization	NAS	J:319681
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TAS	J:169941
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IGI	J:25214
Biological Process	GO:0002157	positive regulation of thyroid hormone mediated signaling pathway	IDA	J:314644
Biological Process	GO:0002157	positive regulation of thyroid hormone mediated signaling pathway	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:314644
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:2326
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NAS	J:320075
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:154828
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:198125
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:198125
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:22384
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:92973
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:22384
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:105576
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:204716
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:105576
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045994	positive regulation of translational initiation by iron	IGI	J:204716
Biological Process	GO:0070564	positive regulation of vitamin D receptor signaling pathway	ISO	J:164563
Biological Process	GO:0060687	regulation of branching involved in prostate gland morphogenesis	IMP	J:78553
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:94471
Biological Process	GO:0031641	regulation of myelination	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:94471
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:23077
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:23077
Biological Process	GO:0051384	response to glucocorticoid	ISO	J:155856
Biological Process	GO:0032526	response to retinoic acid	ISO	J:164563
Biological Process	GO:0032526	response to retinoic acid	IBA	J:265628
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	ISO	J:164563
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	IBA	J:265628
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	IMP	J:204716
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	IDA	J:2326
Biological Process	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	IMP	J:78553
Biological Process	GO:0055012	ventricular cardiac muscle cell differentiation	IGI	J:44836
Biological Process	GO:0055012	ventricular cardiac muscle cell differentiation	IMP	J:44836
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	IMP	J:44836
Biological Process	GO:0061032	visceral serous pericardium development	TAS	J:169941

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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