GO Annotations Graph

• Symbol: Ros1
• Name: Ros1 proto-oncogene
• ID: MGI:97999

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:164563
Molecular Function	GO:0019903	protein phosphatase binding	IPI	J:67582
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IBA	J:265628
Cellular Component	GO:0009986	cell surface	IDA	J:21839
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:21839
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IDA	J:67582
Biological Process	GO:0002066	columnar/cuboidal epithelial cell development	IMP	J:33259
Biological Process	GO:0010467	gene expression	IMP	J:106001
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:85614
Biological Process	GO:0038083	peptidyl-tyrosine autophosphorylation	IDA	J:21839
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IDA	J:67582
Biological Process	GO:0001558	regulation of cell growth	ISO	J:164563
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	IDA	J:67582
Biological Process	GO:0010966	regulation of phosphate transport	IMP	J:85614
Biological Process	GO:0032006	regulation of TOR signaling	ISO	J:164563
Biological Process	GO:0032006	regulation of TOR signaling	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IDA	J:21389
Biological Process	GO:0007283	spermatogenesis	IMP	J:33259
Biological Process	GO:0007283	spermatogenesis	IMP	J:85614
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628