GO Annotations Graph

• Symbol: Rag2
• Name: recombination activating gene 2
• ID: MGI:97849

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:159139
Molecular Function	GO:0003682	chromatin binding	IDA	J:159138
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0035064	methylated histone binding	IDA	J:159139
Molecular Function	GO:0035064	methylated histone binding	IDA	J:159138
Molecular Function	GO:0035091	phosphatidylinositol binding	IDA	J:159138
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	IDA	J:159157
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	IDA	J:159157
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	IDA	J:159157
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	IDA	J:159157
Molecular Function	GO:0005515	protein binding	IPI	J:245396
Molecular Function	GO:0005515	protein binding	IPI	J:159059
Molecular Function	GO:0005515	protein binding	IPI	J:245257
Molecular Function	GO:0043565	sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0008270	zinc ion binding	IDA	J:159138
Molecular Function	GO:0008270	zinc ion binding	IDA	J:159139
Molecular Function	GO:0008270	zinc ion binding	IDA	J:159157
Cellular Component	GO:0097519	DNA recombinase complex	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8865728
Cellular Component	GO:0005634	nucleus	IC	J:159138
Biological Process	GO:0030183	B cell differentiation	IMP	J:1934
Biological Process	GO:0030183	B cell differentiation	IMP	J:1935
Biological Process	GO:0030183	B cell differentiation	IMP	J:76489
Biological Process	GO:0030183	B cell differentiation	IMP	J:121045
Biological Process	GO:0002358	B cell homeostatic proliferation	IMP	J:79297
Biological Process	GO:0002358	B cell homeostatic proliferation	IMP	J:79297
Biological Process	GO:0002326	B cell lineage commitment	IMP	J:31364
Biological Process	GO:0002326	B cell lineage commitment	IMP	J:31364
Biological Process	GO:0002326	B cell lineage commitment	IMP	J:31364
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0042742	defense response to bacterium	IGI	J:88357
Biological Process	GO:1904155	DN2 thymocyte differentiation	IMP	J:65218
Biological Process	GO:0006310	DNA recombination	TAS	J:82340
Biological Process	GO:0002313	mature B cell differentiation involved in immune response	ISO	J:155856
Biological Process	GO:0033085	negative regulation of T cell differentiation in thymus	ISO	J:155856
Biological Process	GO:0035265	organ growth	IMP	J:42039
Biological Process	GO:0035265	organ growth	IGI	J:42039
Biological Process	GO:0046622	positive regulation of organ growth	IGI	J:42039
Biological Process	GO:0046622	positive regulation of organ growth	IMP	J:42039
Biological Process	GO:0002331	pre-B cell allelic exclusion	IMP	J:149451
Biological Process	GO:0030217	T cell differentiation	IMP	J:121045
Biological Process	GO:0030217	T cell differentiation	IMP	J:76489
Biological Process	GO:0033077	T cell differentiation in thymus	IMP	J:1934
Biological Process	GO:0002360	T cell lineage commitment	IMP	J:31364
Biological Process	GO:0002360	T cell lineage commitment	IMP	J:31364
Biological Process	GO:0002360	T cell lineage commitment	IMP	J:31364
Biological Process	GO:0033151	V(D)J recombination	IMP	J:1934
Biological Process	GO:0033151	V(D)J recombination	IMP	J:159138
Biological Process	GO:0033151	V(D)J recombination	IBA	J:265628
Biological Process	GO:0033151	V(D)J recombination	IGI	J:10580